Ying Wang1, Jiade Li1, Chufang Li3,Yi Shi7, Xuanling Shi1, George F. Gao7,Ye Xiang2, Xiangguo Qiu4,5, Ling Chen3,6 & Linqi Zhang1 Ebola virus infections cause a deadly hemorrhagic disease for which no vaccines or therapeutics has received regulatory approval...
The rapid increase of knowledge in recent years about the molecular and cellular bases of immune regulation, particularly at the level of T-cell responses, provides a new arsenal of immunotherapeutic approaches including the development of tumor vaccines. Certain monoclonal antibodies (MABS) were shown...
The level of expression of chimeric antibody should be higher when the gene is at its natural chromosomal location rather than at a random position. Detailed methods for preparation of chimeric (humanized) antibodies can be found in U.S. Pat. No. 5,482,856. 3) Intact Human Antibodies. In...
Furthermore, the treatment of ECs with mAb W6/32 stimulated a higher level of FGFR expression than treatment with serum Abs to individual A locus or B locus molecules, suggesting that the intensity of the signal transduction is related to the aggregation of HLA-I molecules on the cell-surface...