New lasso-shaped antibiotic kills drug-resistant bacteria Antimicrobial molecule discovered in soil from lab technician’s garden — plus, a huge study assessing the nuances of humans’ impacts on biodiversity. Benjamin Thompson Shamini Bundell
Antibiotics: Cooked garlic still kills bacteriadoi:10.1002/scin.5591692318None
An antimicrobial therapy kills or inhibits the growth of microorganisms such as bacteria, fungi, or protozoans. Antimicrobial agents are some of the most widely, and often used therapeutic drugs worldwide. It contributes significantly to the quality of life of many people and reduces the morbidity...
Antibiotics are medicines that help stop infections caused by bacteria. They do this by killing the bacteria or by keeping them from copying themselves or reproducing. The word antibiotic means “against life.” Any drug that kills germs in your body is technically an antibiotic, but most people...
Evybactin is a DNA gyrase inhibitor that selectively kills Mycobacterium tuberculosis. Nat. Chem. Biol. 18, 1236–1244 (2022). This paper describes the discovery of darobactins that target BamA in the outer membrane of Gram-negative bacteria. CAS PubMed PubMed Central Google Scholar Miller,...
Blujepa is bactericidal, which means it kills the bacteria rather than just blocking bacterial growth. FDA approval of Blujepa was based on positive results from Phase 3 clinical studies which demonstrated therapeutic success of 50.6% and 58.5% (with Blujepa) compared to 47% and 43.6% (with...
“We reasoned that harnessing the immune system to simultaneously attack bacteria on two different fronts makes it hard for them to develop resistance,” said Dotiwala. Fluorescence microscopy staining showing the effects of DAIA treatment on bacteria viability. Credit: The Wistar Institute ...
In common usage, anantibiotic(from the Ancient Greek: ἀντί –anti, "against", and βίος –bios, "life") is a substance or compound that kills bacteria or inhibits their growth. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused ...
K. et al. A dual-mechanism antibiotic kills gram-negative bacteria and avoids drug resistance. Cell 181, 1518–1532.e14 (2020). Article CAS PubMed PubMed Central MATH Google Scholar Sidarta, M., Baruah, L. & Wenzel, M. Roles of bacterial mechanosensitive channels in infection and ...
(33) has broad-spectrum antibacterial activity190and kills bacteria through membrane disruption.191Interestingly, LL-37 (33) displayed equipotent activity with its enantiomer D-LL-37, which suggested a nonspecific mode of action, whereas a structure activity relationship study showed that antibacterial ...