951 BETA-LACTAM ANTIBIOTICS: A RISK FACTOR FOR E. FAECIUM-INFECTIONS IN PATIENTS DEVELOPING SECONDARY SCLEROSING CHOLANGITISInfection is a common cause of morbidity and mortality after liver transplantation, which are often caused by Gram negative bacteria and the most frequently occurring infectious ...
Gram-positive bacteremia rates remained unchanged, but more isolates of Enterococcus faecium were resistant to vancomycin after the intervention began. Resistance to the antibiotic agents used in the rotation did not emerge. There was no change in mortality during the intervention period. A ...
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the team inoculated mice orally with different strains of daptomycin-susceptible VR E. faecium. Beginning one day after inoculation, the researchers gave the mice daily doses of either subcutaneous daptomycin, oral daptomycin or a control mock injection for five days...
The beta-lactam antibiotics constitute one of the oldest and most popular classes of anti-bacterial agents. The beta-lactams first used for human therapy, were isolated from molds, particularly Penicillium chrysogenum. The story of the discovery of the a
A child’s first contact with microbes is usually assumed to occur after the rupture of the sterile amniotic sac. However, the placenta and the first stool of infants have been found to contain a full complement of microbes [26,27] and a labeled strain ofEnterococcus faeciumhas been shown ...
Leclercq, R., Derlot, E., Duval, J. & Courvalin, P. Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium. N. Engl. J. Med. 319, 157–161 (1988). CAS PubMed Google Scholar Marshall, C. G., Broadhead, G., Leskiw, B. K. & Wright, G. D. d-Ala...
While Gram-positive pathogens such as VRE and methicillin-resistant Staphylococcus aureus (MRSA) have rightly drawn attention over the past two decades, the Gram- negatives, underlined, in the list of ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter ...
The origin of the term ‘antibiotic’ can be traced back to the wordantibiosefirst used as an antonym to symbiosis by Paul Vuillemin1in his 1890 publication to describe the antagonistic action between different microorganisms (for example, fungi vs bacteria; bacteria vs protozoa).2,3Later, the...
(MIC90 > 8 mg/L). Although itsin vitroactivity againstP. aeruginosaseems seems to be similar to that of imipenem, Biapenem is also active against Gram-positive bacteria, but not against MRSA andE.faecium.It shows the same moderate activity againstE.faecalisas imipenem, meropenem and panip...