In 1976 altered aminoglycoside pharmacokinetics and the need for increased dosage in burn patients was reported but, despite this early study, a review of the currently available literature shows that for many drugs there is a paucity of information to support current dosage recommendations. In ...
Which Are the Best Regimens of Broad-Spectrum Beta-Lactam Antibiotics in Burn Patients? A Systematic Review of Evidence from Pharmacology Studies The aim of this study was to review the evidence for the best regimens of these antibiotics in the burn patient population. Methods: We performed a ....
ObjectiveTo assess the evidence for prophylactic treatment with systemic antibiotics in burns patients. DesignSystematic review and meta-analysis of random... T Avni,A Levcovich,DD Ad-El,... - Bmj 被引量: 111发表: 2010年 Antibiotics and the burn patient Infection is a major problem in burn...
In VAP patients, piperacillin showed good penetration in bronchial secretions [41–43]. Nevertheless, its epithelial lining fluid (ELF) steady-state concentration was lower than the MIC forPseudomonas aeruginosaafter a 4.5-g tid dose [41]. With continuous infusion, an increase in pulmonary concentr...
Clinical experience with prophylactic antibiotic bowel suppression in burn patients. An oral prophylactic antibiotic regimen (--nystatin) aimed at suppression of the bowel flora was utilized in 20 patients with thermal injury treated in a l... RF Jarrett,EJ Moylan,LS Ellerbe,... - 《Surgery》...
In the first part of this study, two groups of 20 patients each are compared. They have been prepared for an elective operation on the colon for neoplastic... A Cazzaniga,G Perazzoli,A Boerchi 被引量: 0发表: 1980年 Antibiotic therapy in surgery of the Colon: Rationale and application Alt...
•Cellwallsynthesisinhibitors•Ribosomefunctioninhibitors•Sulfadrugs•Burntreatmentagents•Miscellaneous Mupirocin(90%PseudomonicacidA)•IsolatedfromPseudomonasfluorescens –AntibacterialactivityofsubstancefromP.fluorescensnotedin1887 –Purifiedinthe1960’s.•MupirocinworksagainstGram-positivebacteriaonly •Can...
For older patients, particularly those who live in long-term care centers, doctors need to use antibiotics when a routine test finds bacteria in lung.3 Throat Diseases 4Therefore, antibiotics shouldn’t be widely used in treatments for such diseases. Only less than one third of strep throats ...
Mainly used for 1. Peptic ulcer bleeding; 2. Acute gastric mucosal damage caused by non-steroidal anti-inflammatory drugs and the occurrence of ulcer hemorrhage under stress; 3. After general anesthesia or major surgery, as well as debilitating coma patients to prevent gastric acid reaction flow ...
Therapeutic drug monitoring of beta-lactam antibiotics in burns patients--a one-year prospective study. Beta-lactams are first-line antibiotics for the management of superficial infections due to burn injury. There is sparse data available on therapeutic drug... Patel, Bhavik M.,J Paratz,See, ...