A multi-center, randomized trial comparing patients with complicated intraabdominal infections found no difference in outcomes between those who received 4 days of antibiotic therapy vs. 8 days after adequate source control.WatkinsDivisionRichardDivisionR.DivisionEBSCO_AspInfectious Disease Alert...
C/T has completed phase II trials in complicated intra-abdominal (cIAI) infections (combined with metronidazole). These data have yet not been published. Phase III trials are ongoing for complicated urinary tract infection, cIAI and hospital acquired pneumonia (HAP). Ceftolozane alone has already ...
Alternatives to antibiotics would, of course, be interesting to explore but ideally, in the case of a bacterial infection, this should be under the supervision of a healthcare practitioner. It is worth considering that antibiotics are not always necessary, for example in the case of viral infec...
Abdominal (stomach) upset: Antibiotics are frequently linked with stomach upset such as nausea, vomiting, lack of appetite (anorexia), stomach pain, or heartburn (dyspepsia). Taking your antibiotic with a snack or a meal may help to decrease stomach upset, if you do not need to take it on...
DATA SYNTHESIS: In total, 23 RCTs met our criteria for inclusion. All trials compared single-agent antibiotics for a short and long antibiotic course in six common infections: community-acquired pneumonia, ventilator-associated pneumonia, intra-abdominal infections, skin and soft tissue infections, ...
What Are Antibiotics? Which Infections Do They Treat? You should notify your doctor if you have any of the following side effects:vomiting, severe waterydiarrhea, abdominal cramps,allergic reaction,rash, vaginal itching or discharge, and white patches on the tongue ...
The pharmacodynamic and pharmacokinetic characteristics of antimicrobial agents are the two fundamental pharmacological components which provide a rationale for the choice of therapy for intraabdominal infections, and especially serious infections. The most important PK-PD parameters are well known which can ...
• Antimicrobial therapy is an adjunct to primary source control procedures in treating patients with intra-abdominal infections. • Therapeutic antimicrobials (those given for longer than 24 h) are required only for patients with established intra-abdominal infections. Patients with limited exposure ...
The most common side effects include nausea, vomiting, diarrhea, abdominal pain. More serious but less common side effects are central nervous system disturbances (headache, confusion, dizziness, tremor), phototoxicity (more common with lomefloxacin and sparfloxacin), prolongation of the QT interval7,...
For E coli intra-abdominal abscess, antibiotics must include anaerobic coverage (eg, ampicillin/sulbactam or metronidazole). In severe infection, piperacillin/tazobactam, ertapenem, or meropenem may be used. Combination therapy with antibiotics that cover E coli plus an antianaerobe can also be used ...