A multi-disciplinary project driven by EMBL Australia researchers at Monash University and Harvard University has found a way to make antibiotics more effective against antibiotic-resistant bacteria — also known as “superbugs.” Antimicrobial resistance to superbugs has been evolving and is one of the...
Which antibiotics are effective against bacteria that lack a cell wall? What causes bacteria to become resistant to antibiotics? What pathogens are resistant to multiple medications? What antibiotics are used for functional medicine? What is the cell arrangement of Salmonella enterica?
Fuda C, Hesek D, Lee M, Heilmayer W, Novak R, Vakulenko SB, Mobashery S: Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus. J Biol Chem 2006, 281:10035-10041....
Interestingly, synthetic antibiotic BE-43472B (41) and its enantiomer (ent-41) exhibited essentially the same potencies against drug-resistant bacteria [that is, 41: MIC=0.083–0.166 μg ml−1 (methicillin-resistant Staph. aureus), 0.33–0.83 (vancomycin-resistant Enterococcus faecalis)...
If S. aureus bacteria infect your body, either through a wound on your skin or through your airways, they can cause serious infections. Warning: this slideshow contains some graphic images. Who Is at Risk for Staph Infections? While anyone can get infected with Staphylococcus, some people face...
Explain how to test for Vancomycin resistance for Staph aureus. Compare and contrast the innate and the acquired immune responses with respect to the time of onset, the immune activators, and the primary immune cell types that involved. Define immunogenicity and explain it...
Daptomycin is used in the treatment of systemic and life-threatening infections of the skin and skin structure, such as Staph aureus bacteraemia, and right-sided Staph aureus endocarditis. It is marketed in the United States under the trade name Cubicin. Side effects include high and low blood...
Scientists discovered a compound in the leaves of a common shrub, the American beautyberry, that boosts an antibiotic’s activity against antibiotic-resistant staph bacteria. Laboratory experiments showed that the plant compound works in combination with oxacillin to knock down the resistance to the dru...
Linezolid showed no significant activity in vivo against the gram-negative pathogens Escherichia coli, Klebsiella pneumoniae, or Moraxella catarrhalis. Linezolid and eperezolid both showed activity against Staph aureus in a mouse with soft-tissue infection,66 although eperezolid was more effective. In...
• 1944: Russian-born microbiologist Selman Waksman, working in the United States with soil microbiologist Albert Schatz, discovers streptomycin, a powerful antibiotic that proves effective against tuberculosis. • 1967: The first penicillin-resistant pneumonococcal bacteria are reported in New Guinea....