The prolonged administration of large doses of penicillin has a toxic effect on the central nervous system, streptomycin affects the acoustic nerve, and so on. These phenomena are treated by reducing the dose. Sensitization may be manifested regardless of the dose or method of administration, and...
Are Ototopical Antibiotics for MRSA Infections Ototoxic?doi:10.1016/j.otohns.2010.06.128KimberleyRutherfordandKatherineKavanaghandKouroshParhamSDOSOtolaryngology Head & Neck Surgery
You have a fast or pounding heartbeat. Your skin or the whites of your eyes turn yellow.When should I contact my healthcare provider?You think you are having an allergic reaction. Contact your provider before you take another dose of your antibiotic. You have a rash. You have a fever. ...
However, the therapeutic concentration of AmAn is close to the toxic concentration, and toxic reactions are prone to occur. Special attention needs to be paid to the peak and trough concentration values when using it. The specific values of therapeutic concentrations and toxic doses of this type...
Abel:True. On the part of the hospital, the pharmaceutical company, the individual physician, and it may actually really not be in the best interest of the patient. And it really took me a long time. I was lucky to be trained by people who are amazing mentors, who I r...
This is important, because Apr is less ototoxic than other AGAs in model organisms, presumably because its antibacterial and anti-mitoribosomal activities are uncoupled7. Moreover, due to its unique structure, Apr is not susceptible to many prevalent resistance mechanisms and is thus a promising ...
In vivo, studies of cell death are typically conducted using mouse models. However, a robust model of aminoglycoside ototoxicity does not exist. Previous studies testing aminoglycoside delivery via intraperitoneal or subcutaneous injection have produced variable ototoxic effects in the mouse. As a ...
Although the chlorination method has a better removal effect on antibiotics, the byproducts generated by the chlorination method are often more toxic, which further limits the research and application of the chlorination method [90]. For example, He et al. [91] found that the antibiotic ...
Phytoremediation is a technique that utilizes plants to remove or transform toxic chemicals incorporated in soils, ground water, and surface water. Various plants are used for removal or degradation of inorganic and organic contaminants, such as pesticides, antibiotics, heavy metals, and nutrients. ...
pustulosis (AGEP), DRESS syndrome (or drug-induced hypersensitivity syndrome, DIHS), as well as multiform and sometimes bullous reactions such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), localized or generalized fixed drug eruptions (FDE), and serum sickness-like symptoms....