Even though the concept of selective inhibition of eukaryotic translation by ribosome-targeting small molecules emerged only recently, it has been long recognized for antibiotics that act upon the bacterial rib
Consider how antibiotics have impacted society, and how society has impacted the use of antibiotics. What was the consequence of that intervention on society? How has society influenced the inception Antibiotics are drugs that selectively kill bacteria without harming animals. Many antibiotics act by ...
We cannot look at this evolving and pandemic threat passively and lose one of the most important drugs discovered in the previous century. We must act now; silence is not an answer. In this position paper, we summarize important messages and conclusions from the 3rd World Healthcare-Associated...
(1989). Influence of antibiotics on biochemical intestinal microflora-associated char- acteristics in man and animals. In: Gillissen G, Opferkuch W, Peters G, Pulverer G. (eds) The Influence of Antibiotics on the Host-Parasite Relationship IIZ. Springer, BerldHeidelberg, pp. 209-21 5....
Some metabolites produced from neighboring microorganisms can also act as chemical elicitors for cryptic BGCs. Therefore, co-culture of multiple bacterial strains could lead to the observation of unprecedented metabolites that could not have been observed by culturing each bacteria individually. As an exa...
To their surprise, the researcher team found that many of these degradation products matched sequences previously identified as antimicrobial peptides – critical components of the innate immune system that act as the body’s first line of defense against bacteria, viruses, and parasites. ...
GT-1 (54) started a phase-I trial (ACTRN12618001980224) in Australia in March 2019 but the trial has been stopped due to safety concerns. There has been no subsequent update about whether development will continue. Apramycin (55) is an aminoglycoside-type protein synth- esis inhibitor being ...
We cannot look at this evolving and pandemic threat passively and lose one of the most important drugs discovered in the previous century. We must act now; silence is not an answer. In this position paper, we summarize important messages and conclusions from the 3rd World Healthcare-Associated...
Some metabolites produced from neighboring microorganisms can also act as chemical elicitors for cryptic BGCs. Therefore, co-culture of multiple bacterial strains could lead to the observation of unprecedented metabolites that could not have been observed by culturing each bacteria individually. As an exa...
The diet should be rich in proteins, since streptomycin lowers the quantity of pantothenic acid (vitamin B3) in the organism, phthavazid and cycloserine act on vitamin B6, and a protein shortage lessens the results of the treatment. Z. V. ERMOL’EVA Use of antibiotics in livestock raising....