The activating sequence directs expression of the aminoglycoside acetyltransferase aac(3)IV and hygromycin phosphotransferase aph(4) genes present on plasmid pKC203. A series of expression vectors have been constructed in which the activating sequence directs the expression of beta-galactosidase or ...
However, antibiotics play a significant role in the induction and dissemination of antibiotic resistance genes (ARGs) in groundwater that has recently become the primary environmental concern. They are administrated to humans and animals on a large scale and are persistent in the environment. Long ...
VE303 high dose associated with reduction in antibiotic resistance genes (ARGs) High VE303 strain colonization also associated with reduced ARGs Presence of ARGs increases the risk of drug-resistant infections Pivotal Phase 3 trial, RESTORATiVE303, underwa...
Widespread prescriptions of antibiotics and use in animal food production have led to a rising prevalence of antimicrobial resistance in the environment. Health experts predict that threats from antibiotic resistance could drastically increase in the coming decades, leading to some 10 million drug-resista...
Some of the detected genes, which are almost certainly not "local" to the Arctic, can confer resistance to multiple drugs. The discovery confirmed the spread of blaNDM-1 (called New Delhi Metallo-beta-lactamase-1) into the High Arctic. ...
Colonization by the microbiota provides one of our most effective barriers against infection by pathogenic microbes. The microbiota protects against infection by priming immune defenses, by metabolic exclusion of pathogens from their preferred niches, an
Antibiotic Resistant Genes in Soil Bacteria 来自 Springer 喜欢 0 阅读量: 35 作者: A Pruden 摘要: The major concern of widespread antibiotic use in agriculture is not necessarily the compounds themselves, but their potential to contribute to the emergence and spread of antibiotic resistance. The...
The rise of community-acquired infections caused by antibiotic resistant bacteria has addressed more interest about the presence of antimicrobial resistance genes (ARGs) in natural environments also including seawaters. It has been well documented a dramatic increase of bacterial resistance to beta-lactams...
Animal fecal samples collected in the summer and winter from 11 herbivorous animals, including sable antelope (SA), long-tailed goral (LTG), and common eland (CE), at a public zoo were examined for the presence of antibiotic resistance genes (ARGs). Seven antibiotics, including meropenem and ...
Whole genome sequencing further uncovered that most isolated phyllosphere protists harbored multiple OHPs which carried antibiotic resistance genes, virulence factors, and metal resistance genes and had the potential to HGT. Colpoda were identified as key phagotrophic protists which positively linked to ...