Linear regression model had an R2 of 0.79 with a p-value of < 0.01. CONCLUSION. The geographic reach of antibiotic prescriptions by outpatient facilities is of concern. The antibiotic burden in surrounding communities is higher than areas further away. Living in an area with high outpatient ...
Children who were RSV+AB+ were significantly older than RSV+AB- (6 vs. 3 months; p = 0.0025) (Table 2). Furthermore, they presented signifi- cantly more often with fever (91.2% vs. 60.6%; p < 0.0001), a septic appearance (48.5% vs. 30%; p = 0.0002), pneumonia (76.8% vs. ...
bovis, Mycobacterium caprae, Mycobacterium microti, Mycobacterium pinnipedii and Mycobacteriuim canettii.26 Of two billion people who are infected with M. tuberculosis, 90% will not develop symptoms but instead serve as a 'reservoir' for the bacterium, thus enhancing the epidemic. TB therapy now...
Microbiota changes Once in the human body, antibiotic residues can inter- act with the human microbiome, which includes a large number of different microorganisms living in the human body. 95% of these microbes are beneficial bacteria, while the rest are harmful bacteria and opportunistic pathogens...
Quality indicators were selected to describe the overall antibiotics use, prescribing patterns and UTIs clinical management regarding treatment and prophylaxis in a cohort of children admitted with a UTI. Microbiological, clinical and prescribing data about dosing, duration and route of administration were...
Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a major global pathogen with limited treatment options1. No new antibiotic chemical class with activity against A. baumannii has reached patients in over 50 years1. Here we report the identification and optimization of tethered macroc...
Fertility was high and did not differ (P > 0.05) between sow groups inseminated with semen stored antibiotic-free at 5 °C and semen stored at 17 °C with antibiotics. Conclusion Despite subtle chilling effects and low bacterial numbers, antibiotic-free hypothermic storage of boar ...
This study evaluated the impact of a novel, antimicrobial test dressing on P. aeruginosa biofilm-infected wounds. Six-mm dermal punch wounds in rabbit ears were inoculated with 10(6) colony-forming units of P. aeruginosa [14]. Biofilm was established in vivo using our published model. ...
4b) and sewage microbiomes between seasons were more heterogeneous than those within either season (t test, P < 0.01) (Fig. 4c). A significant distance-decay effect was also observed—similarity in microbial communities between any two cities decreased with increasing geographic distance (r...
PAS-LuxR is another interesting family of regulators, which contain a N-terminal PAS sensory domain with a C-terminal helix–turn–helix (HTH) motif of the LuxR type. Examples include PimM of pimaricin biosynthesis in Streptomyces chattanoogensis [37], NysRIV of nystatin biosynthesis in S. ...