In c, dashed black lines separate genes with opposing regulatory effects. b, d Heat maps (using yellow-white-blue scale at bottom) show Pearson correlation coefficient (r) matrices measuring relatedness of the corresponding Tn-seq fitness signatures in (a). Positive and negative r indicate ...
fatty acid, or phenyl acetic acid. The structures revealed that the three distinct polypeptide chains generated by self-cleaving activity assemble into a capsule-like higher oligomeric complex
we measured the effects of transposon insertion mutations on bacterial growth during challenge with a broad set of antimicrobial compounds by Tn-seq12. Antibiotics were selected that target a variety of essential cellular processes, with about half of the treatments targeting the cell envelope ...
However, the Chinese revelations as well as several scientific studies have clearly demonstrated that this is not the case. Hot on the heels of the recent pollution scandals, this report documents links between some of the global pharmaceuti- cal industry's biggest household names and dirty ...
determined by the rapid assay. MB45 could change the colour in NHS and HIS tubes at 5 h and therefore inferred as serum-resistant. The control isolate,E. coliK12 could not change the colour of NHS tube even at 8 h, but turned HIS tube yellow at 5 h, was regarded as serum-sensitive...
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