Starting with a curated reference database of genes and SNPs/alleles that confer resistance in historical and contemporary isolates; it is possible to model a framework that predicts the antibiotic resistance profile of an isolate, and project the transition towards resistance over time. Although ...
The misuse and overtreatment of antibiotics in hospitalized patients with community-acquired pneumonia (CAP) can cause multi-drug resistance and worsen clinical outcomes. We aimed to analyze the trends and appropriateness of antibiotic changes in hospita
In order to gain insight into these different bacterial responses and the relationship between them, it is useful to turn to a simple mathematical description, starting with uniform populations. View article Related terms: Agar Agar Plate Inoculum Minimum Inhibitory Concentration Antibacterial Activity Esc...
You may need to stop using certain medicines before using Zyvox (in some cases for up to 5 weeks before starting treatment).During your treatment with Zyvox, do not start or stop using any other medications unless your doctor tells you to. You should not use this medicine at is resistant ...
Starting from theoretical assumptions and giving credit to the intervention of undefined infectious agents and the importance of the participations of the nervous system in the sclerodermas, the author treated 3 cases of generalized scleroderma with sclerodactylia, 4 cases of limited scleroderma and 1...
The pathogen Staphylococcus aureus can readily develop antibiotic resistance and evade the human immune system, which is associated with reduced levels of neutrophil recruitment. Here, we present a class of antibacterial peptides with potential to act bo
Evaluating the quality of antibiotic prescribing patterns using PPS is a starting point for fur- ther improvements within ASPs. The implementation of these PPS aligns seamlessly with national strategies, exemplified by the Lao People's Democratic Republic (PDR) National Action Plan for Elias et al....
[33]. The ProACT trial showed similar result, namely an PCT-based algorithm for starting antibiotics in ICU patients did not reduce their consumption [34]. However, PCT may be useful to withhold antibiotics in patients with suspected, non-severe, community-acquired respiratory infection, such as...
In comparison with ceftazidime, avibactam more strongly potentiates the activity of aztreonam and meropenem in a panel of Bcc clinical isolates. Finally, we characterize in Bcc the iron and receptor-dependent activity of the siderophore-cephalosporin antibiotic, cefiderocol. Our work has implications ...
Mice performed 4 acquisition trials per day starting from four different cardinal points (South, North, East, West; maximal swimming time 120 s; 30 s on platform; inter-trial interval 60 min) during 4 consecutive days. Visual cues were present on the four walls surrounding the pool at a ...