This history has been interpreted to mean that antibiotic resistance in pathogenic bacteria is a modern phenomenon; this view is reinforced by the fact that collections of microbes that predate the antibiotic era are highly susceptible to antibiotics. Here we report targeted metagenomic analyses of ...
M. et al. Antibiotic resistance is ancient. Nature 477, 457–461 (2011). Article CAS PubMed Google Scholar Hernandez, J. et al. Human-associated extended-spectrum β-lactamase in the Antarctic. Appl. Environ. Microbiol. 78, 2056–2058 (2012). Article CAS PubMed PubMed Central Google ...
An unfailing observation over the past 70 years is that resistance to all antibiotics emerges eventually after use in the clinic. Where does this resistanc... GD Wright,H Poinar - 《Trends in Microbiology》 被引量: 0发表: 2012年 Antibiotic resistance is ancient An unfailing observation over th...
The Tibetan Plateau, despite being the highest and least populated plateau on the Earth, harbors antibiotic-resistant bacteria (ARBs) as well as antibiotic resistance genes (ARGs) in its pristine environment and animals. There is, however, limited knowledge regarding antibiotic resistance in Tibetan ...
1). Antibiotic resistance is ancient, ARGs predate the utilization of antibiotics (D'Costa et al., 2011). This is the reason why the incubation time did not impact the number of ARGs and MGEs. Even in the absence of selective pressure caused by antibiotic, manure application could impact ...
resistance to the antibiotics used locally or systemically [55,58]. Additional studies are clearly needed, since the effect of SDD might be greatly influenced by the level of resistance in a given country [55,58]. It should be noted that the follow up of the studies is relatively short. ...
"Antibiotic resistance is an ever-growing problem. In the developing world half of some common infections such as E.coli are now untreatable with available agents. "The most resistant bacteria presently are Acinetobacter and Pseudomonas plus bowel bacteria such as E.coli and Klebsiella. The WHO li...
Essential oils (EOs) are important aromatic components of herbs and spices and their biological activities have been known and utilised since ancient times... MHL Bento,AC Ouwehand,K Tiihonen,... - 《Veterinární Medicína》 被引量: 25发表: 2013年 ...
M. et al. Antibiotic resistance is ancient. Nature 477, 457–461 (2011). Article CAS PubMed Google Scholar Hawkey, P. M. & Jones, A. M. The changing epidemiology of resistance. J. Antimicrob. Chemother. 64 (Suppl. 1), i3–i10 (2009). Article CAS PubMed Google Scholar Pehrsson,...
M. et al. Antibiotic resistance is ancient. Nature 477, 457–461 (2011). This study identifies resistance genes in 30,000-year-old Beringian permafrost sediments, thus providing strong genetic evidence that resistance genes in environmental microorganisms pre-date the anthropogenic use of antibiotics...