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Antibiotic resistance geneEmerging pollutantLCPDb-ARGPCR screeningA literature-based, manually-curated database of PCR primers for the detection of antibiotic resistance genes in various environments was constructed (LCPDb-ARG; lcpdb.ddg.biol.uw.edu.pl and lcpdb.ddlemb.com). Currently, this data...
These go on to reproduce or to transfer their resistance to others of their species through processes of gene exchange. With their more vulnerable competitors wiped out or reduced in numbers by antibiotics, these resistant strains proliferate. The end result is bacterial infections in humans that ...
Further, the expression of some resistance genes is actually induced by the antibiotic, so there is even less cost to the cell for keeping the gene. 2. Antibiotic resistance genes are often located on plasmids or transposons and can be transferred from cell to cell by conjugation, ...
Antibiotic resistance gene (ARG) targets for primer design were chosen and aggregated from two sources. There were 2472 sequences were obtained from the ResFinder database (version 3.2, November, 2016)32, associated with 67 antibiotic resistance families. ResFinder was selected on account of its ma...
Antibiotic resistance, loss of susceptibility of bacteria to the killing (bacteriocidal) or growth-inhibiting (bacteriostatic) properties of an antibiotic agent. When a resistant strain of bacteria is the dominant strain in an infection, the infection ma
Our newly developed ARG database, deepARG-DB, containing predicted ARGs with high confidence and high degree of manual curation, greatly expands the current ARG repository. DeepARG-DB can be downloaded freely to benefit community research and future development of antibiotic resistance-related resources...
Dataandtextmining ARGs-OAP:onlineanalysispipelinefor antibioticresistancegenesdetectionfrom metagenomicdatausinganintegrated structuredARG-database YingYang 1,2,† ,XiaotaoJiang 1,† ,BenliChai 3,† ,LipingMa 1 ,BingLi 1 , AnniZhang 1 ,JamesR.Cole 3 ,JamesM.Tiedje 3, *andTongZhang 1, *...
Better understanding of antibiotic resistance in bovine gut is needed to assess its potential effects based on metagenomic approach and analysis. In this study, we collected 40 fecal samples to explore drug resistance derived from antibiotic use in the bacterial community by an analysis of the ...
ResFinder, a database of mobile, acquired antibiotic resistance genes68 was translated from nucleotide sequences into amino acid sequences using Biopython. The longest ORF for each gene was selected to represent the gene in the database as some genes included upstream and/or downstream regions. ...