The spread of antibiotic resistance is attracting increased attention to combination-based treatments. Although drug combinations have been studied extensively for their effects on bacterial growth1–11, much less is known about their effects on bacteria
Biofilm formation in Staphylococcus aureus causes an increase in antibiotics resistance in chronic diseases, including osteomyelitis, endocarditis, and wound infection. The S. aureus biofilm structure is composed of polysaccharide, protein, and external DNA. Bacterial cells in the biofilm compose of ...
rifampin, interferes withribonucleic acid(RNA) synthesis in bacteria by binding to a subunit on the bacterial enzyme responsible for duplication of RNA. Since theaffinityof rifampin is much stronger for the bacterial enzyme than for the human enzyme, the human cells are unaffected at therapeutic ...
Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis Phelim Bradley, N. Claire Gordon, Timothy M. Walker, Laura Dunn, Simon Heys, Bill Huang, Sarah Earle, Louise J. Pankhurst, Luke Anson, Mariateresa de Cesare, Paol...
Xepi (ozenoxacin) Cream, 1%, a topical non-fluorinated quinolone, approved in December 2017 for impetigo due to Staphylococcus aureus or Streptococcus pyogenes in patients two months of age and older. In Phase III studies, Xepi showed excellent antibacterial activity against S. aureus and S. pyo...
Resistant Staphylococcus aureus (including MRSA) increasingly appears in individuals with no healthcare associated risks. Our study assessed risk factors for nasal carriage of resistant S. aureus in a multinational, healthy, community-based population, including ecological exposure to antibiotics. Data ...
Background and purpose: Staphylococcus aureus is the most common causes of hospital and community acquired infections. Nasal carriage of S. aureus in staff provides a source for infection in hospitalized patients. The aim of this study w... P Afrough,MR Pourmand,N Zeinalinia,... - 《Journal...
AntibioticresistanceoftheStaphylococcusaureusstrainsisolatedfromsputum 系统标签: 耐药性金黄色标本葡萄球菌sputumstaphylococcus 中国感染与化疗杂志2014年5月20日第14卷第3期ChinJInfectChemother,May.2014,Vol.14,No.3·论著·痰标本中金黄色葡萄球菌的耐药性监测刘瑞平1, 曹敏2, 赵建平1摘要: 目的 回顾性分析痰标本中...
This is particularly notable for the Gram-positive bacteria Staphylococcus aureus where the rise of methicillin resistance (MRSA) has led to an increased reliance on last-resort antibiotics. MRSA is widespread, accounting for 37% of S. aureus bloodstream infections and also has higher mortality ...
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