The Study:Double-blinded concealed randomised controlled trial with intention-to-treat.The Study Patients: 322 Finnish children aged 6 to 35 months, diagnosed with acute otitismedia under strict study protocol (middle-ear fluid detected by pneumatic otoscopy, acuteinflammatory signs in the tympanic ...
American Heart Association (AHA) guidelines: Endocarditis prophylaxis recommended only for high-risk patients Bacterial Keratitis (Off-label) 1 drop instilled into affected eye(s) every 1-2 hours; typically alternated every other hour with antibiotic providing gram-negative coverage (e.g., tobramycin)...
For nonsuppurative OM, we excluded index events with an antibiotic eardrop prescription at index for expenditure analyses (eTable 2 in the Supplement). Finally, we restricted the population to the first qualifying event per diagnosis per child (eFigure 1 in the Supplement). Antibiotic Exposure ...