1、抗菌药物概论Introduction to antibacterial drugs,化学治疗(chemotherapy) 应用药物对病原体所致疾病进行预防或治疗称化学治疗简称化疗 病原体包括细菌和其他微生物、寄生虫及癌细胞 化疗药物:化疗过程中所用药物,抗微生物药:抗菌药、抗真菌药、 抗寄生虫药 抗肿瘤药,化疗药物,包括,抗病毒药,机体、抗菌药物及病...
Antibacterial DrugsDavid M. ShlaesInfectious Diseases (Fourth Edition)
The article discusses research being done on antibacterial drugs. It references the study "Activated ClpP kills persisters and eradicates a chronic biofilm infection," by B. P. Conlon. It compares the proteomes of stationary phase Staphylococcus aureus populations with or without ADEP4 and found AD...
Chemotherapy•4.Principlesofapplicationof antibacterialdrugs•5.Mechanismofaction 2021/8/4 1.Overview •Ifbacteriamakeitpastourimmunesystemandstartreproducinginsideourbodies,theycausedisease.•Certainbacteriaproducechemicalsthatdamageordisablepartsofourbodies.•Antibioticsworktokillbacteria.Antibioticsarespecific...
Although still in its infancy, the technology described in this Review may provide the new classes of antibacterial drugs that will be required to fight infection in the twenty-first century and beyond. Abstract The modern era of antibacterial chemotherapy began in the 1930s, and the next four ...
-- Revenue forecasts to 2030 for Antibacterial Drugs Market, with forecasts for Intranasal Antihistamines, Intranasal Corticosteroids, Oral Antihistamines, Immunotherapy and Vaccines, Others, each forecasted at a global and regional level- discover the industry's prospects, finding the most lucrative places...
Nitrofuransare broad-spectrum agents, characterized by effectiveness against both Gram-positive and Gram-negative bacteria, includingSalmonella,Giardia, andSalmonellaspecies,trichomonads,amebae, and some coccidial species. Despite the broad spectrum of activity, otherantibacterial drugsare usually more effective...
Summary Serum concentration measurements of antibacterial agents are increasingly used to optimise drug dosage regimens. However, this approach is only justified for drugs with a low therapeutic index and poor predictability of serum concentrations, such as the aminoglycosides, chloramphenicol and vancomycin...
Mechanisms of selection for resistancePharmacodynamics of antimicrobial drugsPharmacokinetics of antimicrobial drugsEfficacy breakpoints based on concentration–time–effect relationshipsResistance breakpoints based on concentration–time–effect relationshipsPharmacodynamic and pharmacokinetic variability and the requirement ...
FDA Releases Guidance on Systemic Antibacterial Drugs