While controversy still exists as to the precise indications for the treatment of all forms of ventricular arrhythmia, advances in the number and, more importantly, type of anti-arrhythmic drugs can provide the clinician with a rational basis for selecting antiarrhythmic drug therapy. A host of ne...
Tritthart H, Fleckenstein B, Fleckenstein A: Some fundamental actions of anti-arrhythmic drugs on the excitability and contractility of single myocardial fibers. Naunyn Schmiedebergs Arch Pharmacol 269:212–219, 1971. PubMedCASGoogle Scholar Gintant GA, Hoffman BF: Different local anesthetic charact...
the Class I local anaesthetic agents produce central nervous system effects, the Class I drugs with anticholinergic properties produce dry mouth, urinary retention, etc., the Class II antisympathetic agents can lower the blood pressure,
It is axiomatic that the appropriate treatment of arrhythmias requires that each arrhythmia be correctly diagnosed. An awareness of the factors contributing to the arrhythmia, the setting of appropriate therapeutic goals, familiarity with available drugs, and documentation of efficacy are also essential el...