(2007) Engineering zinc finger protein transcription factors to downregulate the epithelial glycoprotein-2 promoter as a novel anti-cancer treatment. Mol. Carcinog., 46, 391-401.Gommans WM, McLaughlin PM, Lindhout BI, Segal DJ, Wiegman DJ, Haisma HJ, van der Zaal BJ, Rots MG: Engineering ...
Certain bacterial zinc-containing anti-sigma (ZAS) factors respond sensitively to thiol-induced oxidative stress by undergoing conformational changes, which in turn reduce binding affinities for their cognate sigma factors. This redox sensitivity provides a mechanism for coping with oxidative stress by ...
(b) catalytic co-factor in DNA synthesis and RNA transcription of hundreds of enzymes such as polymerases, carboxy peptidases, superoxide dismutase, and carbonic anhydrase [9]; and (c) regulatory in protein–DNA interactions of zinc-finger proteins, including many transcription factors [10], ...