1208: IMPACT OF ENOXAPARIN ON ANTI-XA LEVELS WHEN TRANSITIONING TO UNFRACTIONATED HEPARIN INFUSIONdoi:10.1097/01.ccm.0001002996.84540.16Miranda GrahamGeisinger Medical Center, Danville, PAAmber LinkhorstLehigh Valley Health NetworkLaura AndrickGeisinger Medical Center, Danville, PA...
(anti-Xa) level in a cancer patient with heparin resistance.A proven heparin-resistant patient with venous thromboembolism (VTE) and lung cancer who required approximately 66 000 units of unfractionated heparin daily was successfully transitioned to an off-label high-dose enoxaparin (OLHDE) 1.5 mg...
Safety and Effectiveness of an Anti-Xa-based Unfractionated Heparin Protocol for Impella Percutaneous Ventricular Assist Devices Results: Anti-Xa values were in therapeutic range 46% of the time while on support (interquartile range 16.6%-75%), with a median IV UFH dose of ... SE Berman,L ...
Unfractionated heparin (UFH) has unstable pharmacokinetics and requires close monitoring. The activated partial thromboplastin time (aPTT) test has been used to monitor UFH therapy for decades in Korea, but its results can be affected by numerous variables. We established an aPTT heparin therapeutic ...
anti-Xa assayexternal quality assurancelow-molecular weight heparinunfractionated heparinAlthough there is considerable debate regarding the usefulness of laboratory... Bonar,A Roslyn - 《Seminars in Thrombosis & Hemostasis》 被引量: 15发表: 2012年 Stability of low molecular weight heparins stored in ...
UFH unfractionated heparin LMWH low molecular weight heparin 1. Introduction Vascular thrombosis can occur in both arterial and venous circulation and is the leading cause of cardiovascular morbidity and mortality [1]. Heparin is an efficacious anticoagulant widely used for prevention and the treatment ...
Although the activated partial thromboplastin time (aPTT) has historically been the method of choice for anticoagulation monitoring in patients undergoing mechanical circulatory support with intravenous unfractionated heparin, it is being progressively superseded by the anti-factor Xa (anti-Xa) method. A ...
Interlaboratory agreement in the monitoring of unfractionated heparin using the anti-factor Xa-correlated activated partial throm- boplastin time. J Thromb Haemost. 2009;7(1):80-86.Cuker A, Ptashkin B, Konkle BA, Pipe SW, Whinna HC, Zheng XL, Cines DB, Pollak ES. Interlaboratory agreement...
Age, weight, unfractionated heparin dose, Anti-Xa level, and time in relation to dose and calculated creatinine clearance were collected. Patients with a documented adverse event or deep venous thrombosis and pulmonary embolism were recorded. Any patient receiving greater than 5000 units of UFH ...
Venous thromboembolism prophylaxis with subcutaneous unfractionated heparin or low molecular weight heparin is a common practice in hospitalized patients. Typically, prophylactic doses of these medications have poor bioavailability and thus do not reach therapeutic serum concentrations. Howeve...