中文名称:Anti-STING1 antibody-跨膜蛋白173抗体英文名称:STING1 品牌:沪震生物产地:中国/上海 保存条件:-20°C纯度规格:> 99% 产品类别:抗体 一抗 抗体名:Endoplasmic reticulum interferon stimulator; Mediator of IRF3 activation; Mitochondrial mediator of IRF3 activation; N terminal methionine proline tyrosin...
Anti-hSTING-IgG (clone 3B5) is a monoclonal mouse IgG1 antibody against human STING (hSTING). This antibody was generated by InvivoGen using DNA immunization. It has been produced in hybridomas and purified by affinity chromatography. Anti-hSTING-IgG has been selected for its ability to bi...
STING (TMEM173) Antibody, anti-human, PE, REAdye_lease™,130-127-661,美天旎销售价: ¥ 6319.13 /件 市场价: ¥ 7434.27 / 件 在线询价 优惠: 请询价 订货号 : 2AH5574 品牌型号 : 美天旎 130-127-661 货期 : 询货期 最小订货量 : 1件 + - 加入购物车 ...
CAS号: 英文名: STING1 英文别名: STING1 中文名: ANTI-STING1 ANTIBODY-跨膜蛋白173抗体 中文别名: ANTI-STING1 ANTIBODY-跨膜蛋白173抗体 CBNumber: CB113675245 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 ...
Clonality:Monoclonal antibody Clone:3B5 Isotype:Mouse IgG1, kappa Control:Mouse Control IgG1 Source:Hybridoma cells Purity:Purified by affinity chromatography with protein G Formulation:0.2 µm filtered solution in a sodium phosphate buffer with glycine, saccharose, and stabilizing agents ...
Here we demonstrate that tumor cell-directed STING agonist antibody-drug-conjugates (STINGa ADCs) activate STING in tumor cells and myeloid cells and induce anti-tumor innate immune responses in in vitro, in vivo (in female mice), and ex vivo tumor models. We show that the tumor cell-...
antibody Fc region that abrogate FcγR interactions while retaining tumor cell (antigen) binding as well as FcRn binding32(Fig.1c). To study the antigen binding dependency of ADC activity, we generated a non-binding control ADC comprised of the STINGa conjugated to an anti-RSV antibody that...
Fig. 7: TRABID targeting enhances the anti-tumor functions of PD-1 antibody. a Schematic presentation of the experimental workflow. C57BL/6 mice subcutaneously inoculated with B16F10 cells were injected with anti-PD-1 antibody and/or TRABID inhibitor as indicated. b, c Tumor volume at indicat...
While mice treated with either isotype control or a CD4+ T cell-depleting antibody exhibited a 40-50% complete response rate, 0% of mice receiving a CD8+ T cell-depleting antibody survived long-term (Fig. 5d). Finally, SYNB1891-treated animals that had remained A20 tumor-free for at ...
The cell lysates were immunoprecipitated with anti-STING or IgG antibody, and detected by immunoblotting with anti-STING or anti-RIG-I antibody. Data are expressed as mean ± SEM (n = 3). Statistical significance was calculated using Student's t-test or one-way ANOVA; ∗P...