Background Patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) have a two- to threefold greater risk of developing `thrombotic events. The expediency of thrombosis prevention in AAV continues to be discussed. The issue of prescribing anticoagulants (AC) is being ...
Antineutrophil cytoplasmic antibody, Antinuclear antibody, Antiparietal cell antibody, Anti-platelet antibody, Anti-PRP antibody, Anti-Purkinje cell antibody, Anti-receptor antibody, Anti-reticulin antibody, Anti-ribosomal antibody, Anti-Ro/SSA antibody, Anti-single-stranded DNA antibody, Anti-striated mus...
Clinical and experimental data indicate that anti-neutrophil cytoplasmic autoantibodies (ANCAs) cause glomerulonephritis and vasculitis. Here we report the first evidence that complement is an important mediator of ANCA disease. Transfer of anti-myeloperoxidase (MPO) IgG into wild-type mice or anti-MPO...
The invention relates to a blood treatment device configured to remove anti-neutrophil cytoplasmic antibodies (ANCAs) from the blood or blood plasma of a person in need thereof in an extracorporeal blood circuit, wherein the device comprises a matrix, and wherein said matrix comprises a monomeric...
Testicular granulomatous vasculitis mimicking testicular torsion in an anti-neutrophil cytoplasmic antibody–associated vasculitis patient L Suo,LC Perez,CJ Finch - 《Sage Open Medical Case Reports》 被引量: 0发表: 2019年 Role of fine needle aspiration cytology in nonneoplastic testicular and scrotal le...
Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis New Eng J Med., 318 (1988), pp. 1651-1657 Crossref View in Scopus Google Scholar ...
Ma YH, Ma TT, Wang C et al (2016) High-mobility group box 1 potentiates antineutrophil cytoplasmic antibody-inducing neutrophil extracellular traps formation. Arthritis Res Ther.https://doi.org/10.1186/s13075-015-0903-z Tadie JM, Bae HB, Jiang S et al (2013) HMGB1 promotes neutrophil extr...
To gain mechanistic insights into the regulatory effect of PKM2 on PD-L1 expression, we first determined the intracellular localization of PKM2 in dHL-60s under LPS and DASA-58 treatment. LPS treatment induced a significant increase in both the cytoplasmic and nuclear levels of PKM2. DASA-58 pre...
Figure 1.Clinical time course of the present case. CMV; cytomegalovirus, HD; hemodialysis, MPO-ANCA; myeloperoxidase anti-neutrophil cytoplasmic antibody, mPSL; methylprednisolone, PE; plasma exchange, Plt; platelet, PSL; prednisolone. However, on the 17th day after admission, during the induction ...
Multiparameter flow cytometry was used to measure immune complex (IC)-elicited changes in cytoplasmic Ca2+ concentration and initiation of the oxidative burst simultaneously in the same cell and to correlate these with Fc gamma R occupancy. We have previously shown that subpopulations of neutrophils ...