The predictive role of antinuclear antibodies (ANAs) remains elusive in the long‐term outcome of primary biliary cirrhosis (PBC). The progression of PBC was evaluated in association with ANAs using stepwise Cox proportional hazard regression and an unconditional stepwise logistic regression model based...
worldthatanti-nuclearantibodies,especiallyanti-gp210antibody,arecloselyassociatedwithPBC.Itshowedthatanti-gp210antibody hashighspecificityandsensitivityforthediagnosisofPBC,especiallyforthepatientswithnegativeanti-M2antibodytests;inaddition,it hasahighpredictivevaluefortheprognosisanddevelopmentmodelofthedisease.Anti-gp21...
Found in 25% of patients, these antinuclear antibodies must be sought before a strong suspicion of primary biliary cirrhosis with antimitochondrial antibodies negative, as they are highly specific of the disease. They are generally associated with a more aggressive form of PBC.Florent...
Stepwise Cox regression was used to estimate the relationship between anti-gp210 antibodies or ACA and liver transplant (LT)-free survival. The GLOBE scoring system was used to stratify the patients. A total of 1412 patients with confirmed PBC were included in the study. The anti-gp210+ status...
1305 positive anti-gp210 antibodies is a risk factor for poor biochemical response to ursodeoxycholic acid treatment in japanese patients with primary biliary cirrhosisdoi:10.1016/S0168-8278(11)61307-XNakamura, M.Ito, M.Yamamoto, K.Zeniya, M....
The study also found that the combination of AMA/AMA-M2, anti-gp210, and anti-sp100 antibodies had a higher diagnostic sensitivity for PBC compared to any single antibody detection. The authors suggest that CLIA quantitative detection of anti-gp210 and anti-sp100 antibodies can improve the ...
clinical courseanti-glycoprotein 210 antibodyfamilial onsetprimary biliary cholangitisANTICENTROMERE ANTIBODIESCIRRHOSISHEPATITISA 30-year-old woman (daughter) was diagnosed to have primary biliary cholangitis (PBC) with autoimmune hepatitis (AIH) overlap syndrome. Although she was started on prednisolone and...
gp210antibodybiliarylivercirhosisreviewPrimary biliary cirhosis ( PBC ) is a chronic disease characterized by progressive destruction of intrahepatic small bile ducts, which may progress to liver cirhosis. Anti - mitochondrial antibodies, especially anti - M2 antibody, have a high diagnostic value ...
S72Diagnostic Value of Anti-Mitochondrial Antibodies (AMA), Anti-M2, Anti-sp100, and Anti-gp210 in Primary Biliary Cholangitis (PBC)doi:10.14309/01.ajg.0001028656.80979.24Yang, Jane MDAikins, Ato O PhDPunzalan, Rubio MD, PhDAlfego, David PhD...
1109 POSITIVE ANTI-GP210 ANTIBODIES IS A STRONG RISK FACTOR FOR BILE DUCT LOSS AND HEPATITIS WHICH INDUCE JAUNDICE-TYPE PROGRESSION OF PRIMARY BILIARY CIRRHOSIS IN JAPANESE PATIENTSPublication » 1109 POSITIVE ANTI-GP210 ANTIBODIES IS A STRONG RISK FACTOR FOR BILE DUCT LOSS AND HEPATITIS WHICH ...