S. Sait and S. Modak, "Anti-GD2 immunotherapy for neuro- blastoma," Expert Review of Anticancer Therapy, vol. 17, no. 10, pp. 889-904, 2017.Sait S, Modak S. Anti-GD2 immunotherapy for neuroblastoma. Expert Rev Anticancer Ther. 2017;17(10):889-904....
Anti-CD105 antibody eliminates tumor microenvironment cells and enhances anti-GD2 antibody immunotherapy of neuroblastoma with activated natural killer cells. Clin. Cancer Res. 25, 4761–4774 (2019). Article CAS PubMed PubMed Central Google Scholar George, J. et al. Comprehensive genomic profiles ...
Immunotherapy Paediatric cancer Phase I trials Tumour immunology Access through your institution Buy or subscribe Associated content Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis Andras Heczey Amy N. Courtney Leonid S. Metelitsa Nature Medicine Br...
“Neuroblastoma is a cancer of nerve cells which is usually seen as a lump in the abdomen or around the spine. Symptoms may include weakness, bone pain, loss of appetite and fever. Neuroblastoma is the most common solid tumour outside the brain in children. In many cases it is present at...
(9)Combined innate and adaptive immunotherapy overcomes resistance of immunologically cold syngeneic murine neuroblastoma to checkpoint inhibitionJournal for immunotherapy of cancerDecember 6, 2019Voeller J, Erbe AK, Slowinski J, Rasmussen K, Carlson PM, Hoefges A, VandenHeuvel S, Stuckwisch A, Wang ...
CAR-based immunotherapy for breast cancer: peculiarities, ongoing investigations, and future strategies 2024, Frontiers in Immunology Show abstract CAR-T Cells/-NK Cells in Cancer Immunotherapy and the Potential of MSC to Enhance Its Efficacy: A Review 2022, Biomedicines Show abstract Nanotechnology and...
Finally, anti-GD2 is increasingly used for immunotherapy in high-risk NB36. Currently, after surgery, but ongoing trials will assess the advantage of neoadjuvant treatment37,38. Therefore, we also confirmed that anti-GD2-IRDye800CW can still detect NB tissue after upfront anti-GD2 treatment, ...
Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture Yan-Ruide Li Kuangyi Zhou Lili Yang Nature Protocols (2025) Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloi...
In order to determine the general applicability of the ganglioside GD2as a target for immunotherapy, its expression in human cancers has been studied by immunostaining tumor specimens using these monoclonal antibodies. These anti-GD2antibodies reacted with all the neuroblastoma surgical specimens tested ...
Immunotherapy studies have shown that higher survival rates correlate with ganglioside-specific IgM, rather than IgG, for patients vaccinated with a melanoma vaccine (Jones et al., 66 J. Natl. Cancer Inst. 249 (1981)). Consistent with this finding, human studies involving IgM antibodies to ...