Chimeric anti-GD2 antibody with GM-CSF, IL2 and 13-cis-retinoic acid for high-risk neuroblastoma: a Children's Oncology Group (COG) phase 3 study. N Engl J Med 2010; 363: 1324-34.Yu AL, Gilman AL, Ozkaynak MF, et al: Chimeric Anti-GD2 Antibody with GM-CSF, IL2 and 13-Cis ...
Animal models of metastatic ES were attempted in hairless SCID (SHO-PrkdcscidHrhr, RRID: IMSR_CRL:474), NOD SCID (NOD.CB17-Prkdcscid/J) and NSG (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ, RRID: BCBC_4142) mice infusing between 1 million-2 million of TC71 Luc cells. EV and GD2 tCAR MSCs...
kl837Ra02 白介素2受体α(IL2Rα)多克隆抗体 Polyclonal Antibody to Interleukin 2 Receptor Alpha (IL2Ra) kl784Mu02 膜联蛋白A4(ANXA4)多克隆抗体 Polyclonal Antibody to Annexin A4 (ANXA4) kl480Ra01 甘露糖结合蛋白(MBL)多克隆抗体 Polyclonal Antibody to Mannose Binding Lectin (MBL) ...
Two assay methods for quantification of the disialoganglioside (GD2)-specific binding activities of anti-GD2 monoclonal antibodies and antibody immunofusion proteins, such as ch14.18 and hu14.18-IL2, were developed. The methods differed in the use of either microtiter plates coated with purified GD2...
cancers Article The Immunocytokine FAP-IL-2v Enhances Anti-Neuroblastoma Efficacy of the Anti-GD2 Antibody Dinutuximab Beta Nikolai Siebert *,†, Justus Leopold †, Maxi Zumpe , Sascha Troschke-Meurer , Simon Biskupski, Alexander Zikoridse and Holger N. Lode * Department of Pediatric ...
In addition, supernatants from in vitro co-cultures were analyzed using a customized LEGENDplex™ Multi-Analyte Flow Assay (BioLegend), which allowed for the simultaneous detection of human IL2, IL10, IL12 (p70), IL18, granzyme B, IFNγ, perforin, and TNFα. The assay was performed ...