利用anti-GCGR的抗体治疗T1D胰岛素缺陷小鼠,能够将小鼠血糖维持在100mg/dL以下,HbA1c水平低于4%。抑制胰高血糖素作用,结合低剂量胰岛素可以更有效地治疗I型糖尿病。 总的来说,研究人员发现在T1D患病动物中,血糖升高会刺激胰高血糖素分泌,上调磷酸烯醇丙酮酸羧激酶的表达,进一步刺激血糖升高,利用anti-GCGR抗体中和GCGR...
利用anti-GCGR的抗体治疗T1D胰岛素缺陷小鼠,能够将小鼠血糖维持在100mg/dL以下,HbA1c水平低于4%。抑制胰高血糖素作用,结合低剂量胰岛素可以更有效地治疗I型糖尿病。 综述来说,研究人员发现在I型糖尿病患病动物中,血糖升高会刺激胰高血糖素分泌,上调磷酸烯醇丙酮酸羧激酶的表达,进一步刺激血糖升高,利用Anti-GCGR抗体中...
产品名称:Rabbit anti-GCGR (Center) Polyclonal Antibody 产品别名:GCGR抗体 宿主:Rabbit 反应种属:Human;Mouse;Rat 克隆性:Polyclonal Antibody 保存方法:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. ...
Anti-gcgr antibodies and uses thereofThe invention provides anti-GCGR antibodies and methods of using the same.doi:WO2013059531 A1Bernard B. ALLANIsidro HotzelWOWO2013059531A1 * Oct 19, 2012 Apr 25, 2013 Genentech, Inc. Anti-gcgr antibodies and uses thereof...
GCGR, Glucagon receptor, GL-R 应用类型 FCM 免疫原 详情见产品datasheet 来源宿主 Human 反应性 Human 保存建议 详情见产品datasheet 其他 Antibody System Laboratories SAS是一家成立于2019年的法国生物试剂研发品牌,由拥有30多年蛋白抗体开发经验的专家领导。该品牌专注于生产重组抗体、重组蛋白、生物类似药物和RUO...
The dual activity of BI 456906 at the GLP-1R and GCGR was supported using GLP-1R knockout and transgenic reporter mice, and an ex vivo bioactivity assay. Conclusions BI 456906 is a potent GCGR/GLP-1R dual agonist with robust anti-obesity efficacy achieved by increasing energy expenditure and...
300KG steel platform trolley anti-slip steel hand trolley 661LBS light load duty metal bottom hand truck Advantages: 1.Steel platform with anti-slip surface,reinforced steel tube on the platform bottom backside. 2. Three different color f...
Provided herein are methods, compounds, and compositions for reducing expression of GCGR mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate metabolic disease, for example, diabetes, or a symptom thereof.フレアー,スーザン...