点击查看靶蛋白信息: GCGR Accession#:P47871GCGRGene ID:2642 基本信息 产品名称Crotedumab (anti-GCGR), 胰高血糖素受体抗体 别名克罗特度单抗 | 克罗替单抗(抗-GCGR) 英文别名Gcgr antibody | GGR antibody | GL R antibody | GL-R antibody | GLR antibody | GLR_HUMAN antibody | Glucagon receptor ant...
利用anti-GCGR的抗体治疗T1D胰岛素缺陷小鼠,能够将小鼠血糖维持在100mg/dL以下,HbA1c水平低于4%。抑制胰高血糖素作用,结合低剂量胰岛素可以更有效地治疗I型糖尿病。 总的来说,研究人员发现在T1D患病动物中,血糖升高会刺激胰高血糖素分泌,上调磷酸烯醇丙酮酸羧激酶的表达,进一步刺激血糖升高,利用anti-GCGR抗体中和GCGR...
Anti-GCGR Polyclonal Antibody 品牌:solarbio | 货号:K007716P 英文名称 Anti-GCGR Polyclonal Antibody 宿主 Rabbit 别名 GGR 应用 WB IHC 稀释比例 WB 1:200-1000. IHC 1:50-200. 交叉反应 Human Mouse Rat 蛋白分子量 54kDa Gene ID 2642 保存 Store at -20°C. Avoid freeze / thaw cycles. 储存...
Anti-GCGR Polyclonal Antibody 产品说明书 Cat:K007716P Solarbio 宿主:Rabbit 交叉反应:Mouse ; Rat ; Human 应用:IHC ; WB 稀释比例:WB 1:500-2000. IHC 1:10-100. 别名:GCGR, GGR, GL R, GL-R, GLR, GLR_HUMAN, MGC138246, Glucagon receptor precursor ...
Anti-gcgr antibodies and uses thereofThe invention provides anti-GCGR antibodies and methods of using the same.doi:WO2013059531 A1Bernard B. ALLANIsidro HotzelWOWO2013059531A1 * Oct 19, 2012 Apr 25, 2013 Genentech, Inc. Anti-gcgr antibodies and uses thereof...
抗体名:Anti-Human GCGR Antibody (SAA0133) 亚型:IgG4, kappa 是否单克隆:是 免疫原:N/A 用途:仅用于科研 宿主:Human 保质期:1 year 应用范围:FCM 产地:France 标记物:Unconjugate 包装规格:100 μg 品牌:AntibodySystem 抗原来源:N/A 适应物种:Human ...
GCGR, Glucagon receptor, GL-R 应用类型 FCM 免疫原 详情见产品datasheet 来源宿主 Human 反应性 Human 保存建议 详情见产品datasheet 其他 Antibody System Laboratories SAS是一家成立于2019年的法国生物试剂研发品牌,由拥有30多年蛋白抗体开发经验的专家领导。该品牌专注于生产重组抗体、重组蛋白、生物类似药物和RUO...
The dual activity of BI 456906 at the GLP-1R and GCGR was supported using GLP-1R knockout and transgenic reporter mice, and an ex vivo bioactivity assay. Conclusions BI 456906 is a potent GCGR/GLP-1R dual agonist with robust anti-obesity efficacy achieved by increasing energy expenditure and...
Provided herein are methods, compounds, and compositions for reducing expression of GCGR mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate metabolic disease, for example, diabetes, or a symptom thereof.フレアー,スーザン...