Fatty acid synthase and cancer: new application of an old pathway. Cancer Res. 2006;66(12):5977–80. Article CAS PubMed Google Scholar Huang C, Ou R, Chen X, et al. Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating...
If and when such studies in humans become feasible, correlation with FASN protein expression in tumors will need to be closely examined, and may have some significance to therapy response. Although the data we have demonstrated on fatty acid synthase is intriguing and raises the possibility that ...
HFD (HF), or n-3 long-chain polyunsaturated fatty acid (LCPUFA)-enriched HFD (HF/n-3).aGene expression data of the β-adrenergic receptors Adrb3 and Adrb1, which convey the signals from catecholamines to
Met downregulated expression of enzymes of fatty acid de novo synthesis, such as ATP Citrate Lyase (ACLY), Fatty Acid Synthase (FAS), Fatty Acyl-CoA Elongase 6 (ELOVL6), and Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells. In conclusion, CA mediated reprogramming of glucose processing ...
TLR4 overexpression enhances saturated fatty acid–induced inflammatory cytokine gene expression in sheep. Eur. J. Inflamm. 2018, 16, 2058739218792976. [Google Scholar] [CrossRef] [Green Version] Rogero, M.M.; Calder, P.C. Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids. Nutrients...