monoclonalantibodyCancertherapyXenoMouseOverexpression of epidermal growth factor receptor (EGFr) has been demonstrated on many human tumors, and the increase in receptor expression levels has been linked with a poor clinical prognosis. Blocking the interaction of EGFr and the growth factors could lead ...
Humanized anti-EGF receptor monoclonal antibody US7060808 * 1996年6月7日 2006年6月13日 Imclone Systems Incorporated Humanized anti-EGF receptor monoclonal antibodyDevelopment of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy[J] . Xiao-Dong Yang,... NI Goldstein...
Dopamine agonists (DAs) are recognized as first-line therapy;; however, approximately 10% p... YH Gao - 《Open Chemistry》 被引量: 0发表: 2018年 Antibody and how to use them against EGFL7 The invention provides anti-EGFL7 antibodies, and compositions comprising and methods of using these...
In an effort to develop an anti-EGFR antibody suitable for the imaging and therapy of cancer patients, a humanized MAb, h-R3 (the murine form is known as ior egf/r3), was labeled with 99mTc and evaluated for safety and imaging in humans (6-8). A high accumulation of the labeled MAb...
Expert Review of Anticancer TherapyPaul HS, ShawRichard A, Adams. (2011) Where now for anti-EGF receptor therapies in colorectal cancer?. Expert Review of Anticancer Therapy 11 , 1543-1553 /Shaw PH and Adams RA: Where now for anti-EGF receptor therapies in colorectal cancer? Expert Rev ...
: Perspectives of combined radioimmunotherapy and anti-EGFR antibody therapy for the treatment of residual head and neck cancer . Int J Cancer 1998, 77 :13–18.van Gog FB, Brakenhoff RH, Stigter-van Walsum M, Snow GB, van Dongen GA: Perspectives of combined radioimmunotherapy and anti-EGFR...
Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cellsEGF receptor inhibitorsalkylphospholipidsPTENAkttargeted therapyMutational inactivation or deletion of the phosphatase and tensin homologue deleted on chromosome 10 (PTEN)/...
Dual targeting of solid lipid nanoparticles grafted with 83-14 MAb and anti-EGF receptor for malignant brain tumor therapy83-14 monoclonal antibodyAnti-epithelial growth factor receptorBlood-brain barrierGlioblastoma multiformeSolid lipid nanoparticle
Radiolabeling and biological evaluation of DOTA-Ph-Al derivative conjugated to anti-EGFR antibody ior egf/r3 for targeted tumor imaging and therapy. Cancer Biol. Ther. 2005, 4, 854-860.Panwar P, Iznaga-Escobar N, Mishra P, Srivastava V, Sharma RK, Chandra R, et al. Radiolabeling and ...
Monoclonal antibody blockade of EGFR represents a new and exciting direction in cancer therapy.doi:10.1016/j.ijrobp.2003.09.098Kenneth A FoonXiao-Dong YangLouis M WeinerArie S BelldegrunRobert A FiglinJeffrey CrawfordEric K RowinskyJanice P Dutcher...