cell\\|ELISA,4 clones were found to have high affinity to CD5 antigen.DNA sequencing confirmed that the V H fragment is 339 base pairs,the V L 300bp,and the ScFv belongs to the mice gene family.In \\%E.coli\\% HB2151 the soluble ScFv\\|CD5 was expressed mainly in the periplasm....
The murine anti-human CD5 scFv derived from mouse hybridoma cells (clone HI211, which was established in our institute) was cloned into a previously constructed pCDH-CAR plasmid containing the 4-1BB costimulatory domain [35] to form a plasmid referred to as BB.z. Then, the 2B4 intercellular...
To study the radioimmunoimaging ofSm labeledSm-H-OV-5 ScFv and normal mice IgG in nude mice bearing human primary ovarian cancer with three-step pretargetting method, to provide the early diagnosis of ovarian cancer with a new method, and to form the experimental basis for clinical use. ...
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Methods of using these functional monoclonal antibodies include, but are not limited to, detection, quantification, activation, and selective propagation of CAR-modified immune cells.Laurence JN COOPERBipulendu JENASourindra MAITI
已知CD3+CD56+亚群是CIK细胞的主要效应细胞,此亚群的绝大部分细胞都高表达CD5抗原,因此,CD5可以代替CD3作为BsAb的结合靶点.研究发现,抗CD5抗体结合CD5并不促使CIK细胞的过度活化和凋亡,因此,利用它发展的BsAb可望避免CD3抗体诱发的效应细胞过度活化和凋亡现象.本室已成功构建单链抗体(single-chainFv,scFv)anti-CD5...
Anti-Human GZMB Antibody (scFv17) 价格: ¥2300/支 产品详情: Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of profess... 包装规格:100 μg 用途:仅用于科研 用途:仅用于科研 货号:FHC79020 品牌:AntibodySystem 产地:France Anti-Human...
Anti-Human GZMB Antibody (scFv17) 价格: ¥2300/支 产品详情: Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of profess... 包装规格:100 μg 用途:仅用于科研 用途:仅用于科研 货号:FHC79020 品牌:AntibodySystem 产地:France Anti-Human...