ATG-031 and ATG-031-CM were well tolerated in NHP, with toxicities consistent with the mechanism of action and target expression. Conclusions In preclinical studies, ATG-031 demonstrates potent antitumor activity, excellent safety and PK properties, which supports its further development in clinical ...
By preparing a anti-CD98 antibodies novel, this is used, it is possible to provide new therapeutic agents with a new mechanism of action (rheumatoid arthritis or type 1 diabetes) autoimmune diseases. And also, does not inhibit the amino acid transport of CD98, unlike anti-CD98 antibody ...