Anti-CD22 CAR T Cell Therapy Active in R/R Acute Lymphoblastic LeukemiaJason HoffmanPharmD
Promiximab duocarmycin PSMA-ADC PTK7-CPT113 Puxitatug samrotecan Q5-Drug Conjugate Raludotatug Deruxtecan | DS-6000a R-DXd RC108 RC118 REGN2878-DM1 (Anti-PRLR-ADC) REGN3124-PBD REGN5093 - M114 RG-7598 (DFRF 4539A / RG7598 / RG 7598) ...
英文名称: Anti-CD19/CD22 Bispecific CAR Lentivirus (Clones FMC63/m971 ScFv-CD8-4-1BB-CD3ζ) 总访问: 64 国产/进口: 进口 半年访问: 9 产地/品牌: BPS 产品类别: 其他生物试剂 规格: 50 μl 最后更新: 2024-12-5 货号: 78609 CAS 号: 参考报价: 15330 立即询价 电话咨询 ...
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Chimeric antigen receptor (CAR) T-cell immunotherapies targeting CD19 can achieve impressive clinical remission rates in the treatment of B-cell non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia. However, relapse after CD19-CAR T treatment remains a major issue, with CD19 antigen-negativ...
Introduction: UCART22 is a genetically modified allogeneic T-cell product manufactured from non-HLA matched healthy donor cells. Donor-derived T-cells are transduced using a lentiviral vector to express the anti-CD22 chimeric antigen receptor (CAR; anti-CD22 scFv-41BB-CD3ζ) and are further mod...
The present invention relates to an engineered immune cell endowed with a new CD22 Chimeric Antigen Receptors (CD22 CAR) with a deletion in the TRAC gene that is able to redirect said immune cell specificity and reactivity toward selected tumor cells. The engineered immune cells endowed with ...
High Remission Rate From Anti-CD22 CAR T-Cell Therapy in Pediatric ALLJason M. Broderick
Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteinsT cellsCHIMERIC proteinsdoi:10.1038/s41408-021-00499-zFranziska BlaeschkeDana StengerAntonia ApfelbeckBruno L. CadilhaTobias FeuchtingerBlood Cancer Journal...
The present invention relates to an engineered immune cell endowed with a new CD22 Chimeric Antigen Receptors (CD22 CAR) with a deletion in the TRAC gene that is able to redirect said immune cell specificity and reactivity toward selected tumor cells. The engineered immune cells endowed with ...