a 105kDA cell surface molecule consisting of extracellular leucine rich repeats (LCC) and a short cytoplasmic tail also known as Bgp-95 and RP105. CD180 is expressed on B cells, dendritic cells, monocytes, and macrophages. It forms a cell surface receptor complex with MD-1 and with TLR4 ...
产品编号: 13-1809-82 查看说明书 产品名称: Biotin anti-human CD180 (RP105, Toll-like Receptor/ TLR Family) 100 ug .0 订购此产品 供应商: Ebioscience 规格: 100 ug 目录价: 2628 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址: 点击查看详细 打印此页 ...
B cells activated by RP105-ligation arrest their growth and undergo apoptosis when the antigen receptor is engaged. The RP105/MD-1 complex in concert with TLR4 mediates B cell recognition and signaling of LPS. Thus, RP105 is a signal transduction molecule and plays a role in regulation of ...
品牌型号:美天旎 130-127-180 货期:询货期 最小订货量:1件 +- 美天旎 联系我们 400-920-3909 微信扫一扫,手机采购 产品介绍Product Description Clone REA649 recognizes the human CD184 antigen, a multi-pass membrane protein, also known as C-X-C chemokine receptor type 4 (CXCR4), leukocyte-deriv...
maintaining B-cell tolerance and in preventing autoimmunity. In mast cells negatively regulates high affinity immunoglobulin epsilon receptor signaling.independent of SH2D1A and SH2D1B but implicating FES and PTPN6/SHP-1. In macrophages enhances LPS-induced MAPK phosphorylation and NF-kappaB activation ...
PD analyses included immunohistochemistry, enzyme activity assays in tumor biopsies, and evaluation of receptor occupancy and soluble CD73 in peripheral blood.Results: As of the Dec 19, 2017, data cutoff, 59 pts were treated with BMS-986179 卤 NIVO during dose escalation. PK of BMS-986179 was...
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产品名称: Functional Grade Purified anti-mouse CD180 (RP105, Toll-like Receptor/ TLR Family) 100 ug .0 订购此产品 供应商: Ebioscience 规格: 100 ug 目录价: 2628 库存状态: CAS编号: 应用范围: 种属来源: 相关信息: 保存条件: 说明书地址: 点击查看详细 打印此页 关闭此页 上一个:Fu...
B cells activated by RP105-ligation arrest their growth and undergo apoptosis when the antigen receptor is engaged. The RP105/MD-1 complex in concert with TLR4 mediates B cell recognition and signaling of LPS. Thus, RP105 is a signal transduction molecule and plays a role in regulation of ...
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