The mAb consisted of rituximab (R), anti-CD20 with enhanced affinity for CD20 (AME-B), and anti-CD20 with enhanced affinity for both CD20 and CD16 (AME-D). Higher concentrations of mAb were needed to induce CD16 modulation, CD54 up-regulation, and antibody-dependent cellular cytotoxicity ...
PIERCEMA133495Anti-CD16 Monoclonal Antibody50 µl2450 厂商 货号 品名 规格 目录价 库存状态 PIERCE MA133495 Anti-CD16 Monoclonal Antibody 50 µl 2450 PIERCE MA133498 Anti-CD20 Monoclonal Antibody 200 µg 5498 PIERCE MA133501 Anti-CD16 Monoclonal Antibody 1 ml 6056 PIERCE MA133502 Anti...
Dimorphism in CD16 might influence the therapeutic response to rituximab, which is an anti-CD20 humanized immunoglobulin G1 extensively used in the treatment of non-hodgkin lymphomas. Mutation in the gene might lead to natural killer (NK) cell immunodeficiency. Features and Benefits【特点和优势】 ...
In addition, the FcγRIIIA-optimized LFB-R603 anti-CD20 mAb mediates 100 times greater antibody-dependent cell-mediated cytotoxicity by NK cells from CLL patients and healthy donors than rituximab. Enhanced degranulation against autologous B-CLL cells is observed at lower concentrations of LFB-R...
Bispecific killer cells engagers (BiKEs) which can bind to natural killer (NK) cells through the activating receptor CD16A and guide them to cells expressing the HIV-1 envelope glycoprotein (Env) are a promising new weapon for elimination of infected cel
Anti-CD20 Ab therapy has proven successful for treating B cell malignancies and a number of autoimmune diseases. However, how anti-CD20 Abs operate in vivo... F Montalvao,Z Garcia,S Celli,... - 《Journal of Clinical Investigation》 被引量: 200发表: 2013年 Antibody-mediated B-cell depletion...
Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab. Blood. 2006; 108 :2648–2654.Bowles JA, Wang SY, Link BK, Allan B, Beuerlein G, Campbell MA, et al. Anti-CD20 monoclonal antibody with enhanced ...
PIERCE MA180838 Anti-CD79b Monoclonal Antibody, RPE conjugate 100 Tests 1769 PIERCE MA180839 Anti-CD20 Monoclonal Antibody 200 µg 3741 产品留言 标题 联系人 联系电话 内容 验证码 点击换一张 注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!2.如有必要,请您留下您的详细联系方式! 相...
In vivo xenograft studies demonstrated that a single low-dose regimen of engineered hnCD16FR iPSC-derived NK cells co-administered with anti-CD20 mAb treatment mediated potent activity and significantly improved survival. Conclusion: We developed a novel hnCD16FR construct that exhibits more potent ...
Analysis of CD16+CD56dim NK cells from CLL patients: evidence supporting a therapeutic strategy with optimized anti- CD20 monoclonal antibodies. Leukemia. ... 被引量: 33发表: 0年 Brain size and brain organization of the whale shark, Rhincodon typus, using magnetic resonance imaging. Very little...