近日,中国海洋大学医药学院分子合成中心的徐涛教授团队关于Type II [4+4]型高张力桥环构建的研究成果,以“Regioselective activation of benzocyclobutenones and dienamides lead to anti-Bredt bridged-ring systems by a [4+4] cycloaddition”为题,发表于Nature系列学术期刊《Nature Communications》(《自然·通讯》...
An "anti-Bredt" bicyclic urea, 1,3-diazabicyclo-[3.3.1] nonan-2-one, was synthesized. At 125° this urea polymerized thermally and at 98° it rapidly polymerized under the influence of phosphoric acid. Two isomeric ureas, lacking the anti-Bredt feature, did not polymerize under similar ...
Anti-Bredt Enol Ethers by Transannular Cyclization of Cycloalkynolsrearrangementsring closure reactionsmulti-membered O,S-heterocycles (O or S ring membersChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access ...
Hall, Jr. et al, Anti-Bredt Bridgehead Nitrogen Compounds in Ring-Opening Polymerization, Chemical Reviews, vol. 83, Issue 5, 1983, pp. 549-555.Hall H. K. Jr. et al., Anti-Bredt Bridgehead Nitrogen Compounds in Ring-Opening Polymerization, Chemical Reviews, 1983, vol. 83(5), pp. ...
ones (BCBs) has emerged as an attractive approach for preparing fused- and bridged ring systems pioneered by Liebeskind34and Dong35,36(Fig.1d). However, no catalytic [4 + 4] annulation via oxidative C–C activation has been known, not to mention forming the highly strained anti-Bredt...
近日,中国海洋大学医药学院分子合成中心的徐涛教授团队关于Type II [4+4]型高张力桥环构建的研究成果,以“Regioselective activation of benzocyclobutenones and dienamides lead to anti-Bredt bridged-ring systems by a [4+4] cycloaddition”为题,发表于Nature系列学术期刊《Nature Communications》(《自然·通讯...
1-Aza-3-oxabicyclo[3.3.1]nonan-2-one, an N-bridgehead bicyclic urethane, polymerized in bulk under the influence of dibutyltin oxide and p-toluenesulfonic acid. In solution the monomer polymerizes in the presence of phosphoric acid. This is only the second example of ring opening ...
Bicycloalkenones can be generated by intramolecular Wittig-reaction, even if the olefinic bond formed has a relative high strain energy.doi:10.1016/S0040-4039(00)87664-9Hans Jürgen BestmannGerold SchadeElsevier BVTetrahedron Letters
Model anti-Bredt strain alkene (mol mechanics poor)Novak, I
MartinD.BertrandG.ingentaconnectChemical Communications Royal Society of ChemistryAnti-bredt N-heterocyclic carbene an efficient ligand for the gold (I)-catalyzed hydroamination of terminal alkynes with parent hydrazine. López-Gómez M J,Martin D,Bertrand G. Chemical Communications . 2013...