ACROBiosystems百普赛斯的Anti-C11D5.3 scFv Antibody，经过流式细胞术批检验证，具有卓越的高灵敏度和高特异性，是检测CAR表达、CAR细胞质控及CAR细胞药代动力学分析的理想工具。无抗原阻断干扰：该抗体为非中和型抗体，能够在不干扰C11D5.3 scFv与其靶抗原BCMA结合的前提下，精确检测C11D5.3 scFv的总量。无干扰...
凭借李宗海博士及其团队在 CAR-T 细胞疗法领域多年的深厚积累,科济药业开发了全人抗 BCMA 自体 CAR-T 产品 CT053。经过基因修饰,CT053 可表达融合了具有高亲和力的全人源 BCMA 特异性单链片段(scFv)25C2 的 CAR,其免疫原性降低而安全性提高,兼具了良好的疗效和安全性,相继获得了美国 FDA 的“再生医学先进疗法...
英文名称: Anti-BCMA CAR Lentivirus (Clone C11D5.3 ScFv-CD8-4-1BB-CD3??) 总访问: 78 国产/进口: 进口 半年访问: 12 产地/品牌: BPS 产品类别: 其他生物试剂 规格: 50 μl 最后更新: 2024-12-5 货号: 78655 CAS 号: 参考报价: 15330 立即询价 电话咨询 ...
The Fd fragment and LC from an anti-BCMA antibody are both extended with the scFv fragment from an anti-CD3 antibody This BsAb can retarget T cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy. Datasheet INQUIRY Specifications Targets BCMA & CD3 ...
Provided are an anti-BCMA single-chain antibody scFv and a preparation method and application thereof. The preparation method is capable of artificially synthesizing a BCMA-targeted phage display library by combining site-directed mutagenesis and random mutagenesis technologies; and acquiring 3 new-type...
33. Unlike a scFv, single heavy-chain-only binding domains have no need for a potentially immunogenic linker to connect the heavy chain to the light chain. Because human heavy-chain-only antigen-recognition domains have no linker or light chain, two potentially immunogenic junctions that must be...
Customer Reviews and Q&As There are currently no customer reviews or questions for Recombinant Anti-BCMA x Anti-CD3 Bispecific Antibody (scFv-Fc-scFv) (BSTF-020). Click the button below to contact us or submit your feedback about this product....
背景 靶向BCMA CAR-T细胞 BCMA即B细胞成熟抗原,其在浆细胞和分化的浆细胞表面特异性表达,而在记忆性B细胞、未成熟B细胞、CD34+造血干细胞和其他正常组织细胞中不表达。BCMA已成为多发性骨髓瘤(MM)和其他血液恶性肿瘤(霍奇金淋巴瘤、非霍奇金淋巴瘤、胶质母细胞瘤等)的一个非常热门的免疫治疗靶点。目前,全球已有...
目的:通过对CAR结构的ScFv单链可变区进行改造,构建并筛选具有更强杀伤肿瘤细胞功能的新型靶向人源B细胞成熟抗原(BCMA)的嵌合抗原受体(CAR)-T细胞.方法:构建靶向人源BC... 崔鑫铭,董宇曦,尚凤琴,... - 《现代生物医学进展》 被引量: 0发表: 2024年 靶向BCMA的仿生光热纳米药物在多发性骨髓瘤中的治疗研究 并...
BCMA & TACI Customer Reviews and Q&As There are currently no customer reviews or questions for Recombinant Human Anti-BCMA x Human Anti-CD3 Bispecific Antibody (scFv-CH3) (BSFC-H200). Click the button below to contact us or submit your feedback about this product. ...