FUNCTION: SwissProt: Q13131 # Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of
The bioinformatic analysis results showed that the anti-inflammatory function is possibly due to the inhibition of NF-魏B signaling. And this result is confirmed by using immunocytochemistry. Moreover, this effect can be suppressed by the AMPK inhibitor. Results also showed that adenine can activate...
MAPKsPI3KAktmTORAkt protein kinase BAMPK adenosine 5′-monophosphate-activated protein kinasePI3K phosphoinositide 3-kinaseTo evaluate the anti-inflammatory function of mogroside V (MGV) and its molecular mechanism, dextran sulfate sodium (DSS)-induced colitis and lipopolysaccharide (LPS)-induced ...
Addition, SH200 also improved mitochondrial function and protected muscle fibers via AMMPK/PGC-1伪 signal pathway. Thus, the SH200 is a potential candidate natural agent that could be used to reduce physical fatigue.doi:10.1016/j.jff.2019.103489Yuanyuan Zhang a b...
The rotarod test was firstly developed to screen neurologic effects of drugs and then it became a useful device for evaluating motor function (Hamm, Pike, O’Dell, Lyeth, & Jenkins, 1994). Fatigue was one of the factors to inhibit rotarod performance (Kuribara, Higuchi, & Tadokoro, 1977)...
Additionally, evidence suggests potential protective effects of RIC against retinal ischemia, improving the survival and function of retinal neurons in diabetic retinopathy and glaucoma [15,16]. We reported previously that RIC therapy is protective following TON by preventing retinal ganglion cell (RGC)...