Peroxidase(TPO)AutoantibodiesinHumanSerumorPlasma byaMicroplateEnzymeImmunoassay.MeasurementsofTPO autoantibodiesmayaidinthediagnosisofcertainthyroid diseasessuchasHashimoto’sandGrave’saswellasnontoxic goiter. SUMMARYANDEXPLANATIONOFTHETEST Antibodiestothyroidperoxidasehavebeenshowntobe ...
Methods: detected Anti-TPOA, Anti-TG, TSH, FT4 and FT3 in the blood serum of 270 HT cases, including 100 cases with normal thyroid function, 83 cases with hypothyroidism and 87 cases with hyperthyroidism using the immunoassay of chemical luminescence micro particles; and detected the contents ...
Blood samples were collected under aseptic conditions and were sent to one laboratory for thyroid function tests and anti-TPO antibody test by ELISA. Results In this study abnormal TFTs were seen in 7(9.1%) patients. Among these patients 2(28.6%) were diagnosed as hyperthyroid and 5(71.4%)...
A protein produced in the blood or tissues in response to the presence of a specific foreign antigen. Antibodies provide immunity against certain microorganisms and toxins by binding with them and often by deactivating them. Also calledimmunoglobulin. ...
Human thyroid peroxidase (TPO) has been purified from thyroid microsomes by immunoaffinity chromatography using a monoclonal antibody (mAb) to TPO. The elu... B Czarnocka,J Ruf,M Ferrand,... - 《Febs Letters》 被引量: 559发表: 1985年 Proliferative Responses of Peripheral Blood Mononuclear Cell...
TPO as antigen demonstrated its specificity, practicability and reproducibility in screening of anti-TPO autoantibodies in sera of autoimmune thyroid patients. ... H Haubruck,L Mauch,NJ Cook,... - 《Autoimmunity》 被引量: 31发表: 1993年 Significance of anti-α-fodrin antibody in the diagnosis ...
The heart was excised quickly, and cardiac atrium, blood vessel, adipose tissue and thymus were cut off, immerged in PBS solution (0.02 mmol/L, PH = 7.4), frozen in −20°C for 1 h and sliced into 2–3 mm thick sections perpendicular to the long axis of the heart. Slices ...
Blood tests measured anti-TPO levels. Disease activity was assessed by urticaria activity score (UAS-7) and quality of life impairment was assessed by DLQI and CU-Q(2)oL. There were no statistically significant differences between ASST (+) and ASST (-) and also APST (+) and APST (-)...
Cell viability was assayed by the MTT test as pre- bviyo5u0s%ly,dinesccormibpedar.2i1soTnhewIiCth50cewllasstdreeafitnededwaitshththeecmomaxpiomuunmd concentration required to amount of DMSO (0.25%) inhibit cell proliferation and considered as 100% viability. Peripheral blood lymphocytes (PBL)...
We show here that anti-TPO aAb B40 purified from CHO is able to induce a moderate cytotoxic activity, lower than that of patients' circulating anti-TPO aAbs on the papillary carcinoma cell line NPA, whatever the effector cells used (peripheral blood mononuclear cells (PBMC) or monocyte cell ...