上海玉博生物科技有限公司 主要致力于“Human anti-ribonucleo protein Antibody,RNP-Ab ELISA Kit ”的生产销售。多年的“Human anti-ribonucleo protein Antibody,RNP-Ab ELISA Kit ”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司经营的产品名称深受
The population of ANAs detectable by nucleus ELISA included anti-ss-B/La, anti-DNA, anti-histone, anti-Sm, anti-RNP, and anti-scl-70.doi:10.1002/jcla.1860050109TomofumiLaboratoryJitsukawaLaboratorySatokoLaboratoryNakajimaLaboratoryJunkoLaboratory
RNP complexes were generated according to the manufacturer’s protocol using HiFi Cas9 (IDT) and transfections were performed using lipofectamine 2000 (ThermoFisher). For siRNA transfections, we used the Rab32 siGENOME (Horizon Discovery, SMARTPool, M-009920-02-0005) and the non-targeting siRNA ...
a AT3 control cells (Ctl sgRNA: n = 10) or those in which PTPN2 had been deleted by CRISPR RNP (Ptpn2 sgRNA: n = 10) were injected into the fourth inguinal mammary fat pads of 8-week-old female C57BL/6 mice and tumor growth was monitored. b Tumor-infiltrating lymphocytes...
CD8+T cells. In (a–e) representative results (means ± SEM) from at least two independent experiments are shown. Significance for tumor sizes in (a) was determined using a 2-way ANOVA Test and for tumor weights in (b) and for TILs in (c–e) using a 1-way ANOVA Test. In ...
Ma et al, “Antibody penetration of viable human cells. 1. Increased penetration of human lymphocytes by anti-RNP IgG”, Clin Exp Immunol 84:833-8 91 (1991) Madaio et al, “Spontaneously produced anti-DNA/DNase I autoantibodies modulate nuclear apoptosis in living cells. Eur J Immunol 26:...
AcrIIA6 strongly interacted with St1Cas9 RNP, as shown by their very slow dissociation rate that indicates the formation of a quasi-irreversible complex (Figure 1A). On the other hand, AcrIIA6 did not bind to apo-St1Cas9, apo-Streptococcus pyogenes Cas9 (apo-SpCas9), or SpCas9 RNP. We...
Repurposed CRISPR-Cas molecules provide a useful tool set for broad applications of genomic editing and regulation of gene expression in prokaryotes and eukaryotes. Recent discovery of phage-derived proteins, anti-CRISPRs, which serve to abrogate natural
(a) for tumor types significantly associated with poor survival are plotted as Kaplan Meier curves (Likelihood ratio – Cox proportional hazard model). Insets show a range ofTRA2β-PEPSI across all samples (boxplots: median±quartile ranges; red: low inclusion; gray: other; Wilcoxon test, *...
P-Prot. Sm Ku U1-RNP Scl-70 CENP-A,B,C RNA-Polym. Fibrillarin To/Th NOR-90 PM-Scl Mi-2 mögl. Erkrankung systemischer lupus erythematodes Sjögren- Syndrom mixed connective tissue disease system. Sklerose Poly-/Dermato- myositis SRP Jo-1 etc.* mitochondr. M2 Sp 100 Anti-Synthetase...