Two sisters with clinical elements of mixed connective tissue disease were found to have anti-nuclear RNP (nRNP) antibodies. These antibodies were not found in the six other family members examined. The sisters had inherited an identical HLA haplotype A2-BW61CW3-DR1 from their mother who had ...
Antibodies to RNP-70, the 70 kDa protein of the U1-RNP complex show the highest diagnostic sensitivity for MCTD, their absence completely rules out this disease. Up to 32% of patients with SLE and up to 10% of patients with systemic scleroderma present with detectable anti-RNP-70 titers. ...
Anti-SIRT1/FITC 荧光素标记沉默调节1抗体IgGMulti-class antibodies规格: 0.2ml Rhesus antibody Rh phospho-P53(Thr55) 磷酸化抑制基因P53抗体 规格 0.1ml Bassoon(BSN) Multi-class antibodies规格: 0.5mg Anti-rRNP抗核糖体抗体elisa酶联免疫试剂盒Bacillus amyloliquefaciens丝裂原活化激酶激酶6 Bacillus amy...
4) Anti-RNP antibodies (Speckled or Nucleolar Pattern) a) Specifically for the differential diagnosis of: 1. Systemic rheumatic diseases 2. Follow-up analysis of collagen vascular disorders 5) Anti-SSA and Anti-SSB (Speckled Pattern) a) Valuable when a patient is anti-nuclear antibody ...
[36–41]. There is evidence that NETosis has a stronger association with LN than SLE without LN. Persistence of NET burden is associated with LN as well as elevated dsDNAab and anti-NET antibodies [37]. Netting neutrophils present in kidney biopsies are specifically associated with PLN and ...
Patients with anti-RNA polymerase III antibodies were 6 times more likely to have a cancer within 3 years following the first signs of scleroderma [51]. Anti-U1RNP antibodies are found in 90% of mixed connective disease and are often associated with the presence of other antibodies (anti-SSA...
Antibodies, Antinuclear, Anti-DNA, Anticentromere, Antiextractable Nuclear Antigen, Anti-Jo, and Antiscleroderma Synonym/acronym: Antinuclear antibodies (ANA), anti-DNA (anti-ds DNA), antiextractable nuclear antigens (anti-ENA, ribonucleoprotein [RNP], Smith [Sm], SS-A/Ro, SS-B/La), anti-...
Both competing and cross-competing antibodies are encompassed by the present invention. The term “competitor” antibody can be applied to the first or second antibody as can be determined by one of skill in the art. In some cases, the presence of the competitor antibody (e.g., the first ...
Recent clinical observations have assigned increased significance to the anti-Sm and anti-RNP antibodies found in the sera of patients with systemic lupus erythematosus (SLE) t and certain other related disorders. The anti-Sm antibodies are highly specific for SLE, whereas the anti-RNP antibodies ...
The goals of the current work are: 1) to examine the epidermal deposition of anti-RNP IgG human autoantibodies in neonatal BALB/c mice; 2) to look for immunoregulatory effects of anti-idiotypes allowing one to inhibit the epidermal deposition of anti-RNP antibodies; and 3) to elicit antinucle...