Results. Themost common form is anti-NMDA receptor encephalitis, a severe brain disorder with characteristic clinical development of symptoms, including psychosis, hyperkinesia, autonomic instability, epileptic seizures, and memory impairment. In addition, recognition of antibodies against LGI1, Caspr2, ...
Anti-NMDA Receptor Encephalitis Antibody Binding Is Dependent on Amino Acid Identity of a Small Region within the GluN1 Amino Terminal Domain Anti-NMDA receptor (NMDAR) encephalitis is a newly identified autoimmune disorder that targets NMDARs, causing severe neurological symptoms including hallu... AJ...
NMDAR encephalitis is a common cause of autoimmune encephalitis, predominantly affecting young adults. Current data supports the idea that autoantibodies t... A Venkatesan,K Adatia - 《Acs Chemical Neuroscience》 被引量: 7发表: 2017年 Could coenzyme Q10 supplementation have a role in the treatment...
Within NMDAR encephalitis, typical MRI changes include white matter changes within diffusion tensor imaging (DTI), which are most often found in the cingulum and correlate with disease course [37]. However, normal MRI results even with severe clinical symptoms are a well-known phenomenon in a maj...
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a treatable autoimmune disorder characterized by prominent neuropsychiatric symptoms that predominantly affects children and young adults. In this review, we discuss the pathogenic mechanisms and immunologic triggers of anti-NMDAR encephalitis,...
Anti–NMDAR encephalitis in a patient with Crohn disease receiving adalimumab 来自 Semantic Scholar 喜欢 0 阅读量: 22 作者:GP Noble,L Eric 摘要: Anti–tumor necrosis factor alpha (TNF-α) therapies have been a significant advance in the treatment of autoimmune and rheumatologic diseases. Early ...
Soluble forms of Intercellular adhesion molecule‐1 (sICAM‐1), vascular adhesion molecule‐1 (sVCAM‐1), and L‐selectin (sL‐selectin), were measured in the CSF and serum of 26 participants with anti‐NMDAR encephalitis, 11 patients with schizophrenia and 22 patients with noninflammatory ...
We report a case of a confirmed non-paraneoplastic anti-NMDAR encephalitis with a rather classical manifestation in a Latvian woman who is first hospitalized in a psychiatric clinic then transferred to an ICU (intensive care unit), treated with glucocorticoids, plasma exchange and later ...
2 1Department of Psychiatry and Behavioral Neuroscience, 2Department of Neurology, University of Chicago, Chicago, IL, USA Objective: Anti-N-methyl-d-aspartate-receptor (NMDA-R) encephalitis is a new autoimmune disorder, often paraneoplastic in nature, presenting with complex ne...
Relapses did not add residual deficit to that caused by the first episode.Relapses in anti-NMDAR encephalitis are common (24%). They may occur many years after the initial episode. Relapses may present with partial aspects or with isolated symptoms of the full-blown syndrome. Immunotherapy at...