Anti-MuSK positive myasthenia gravis (MuSK-MG) is rare prepuberty. We report a female patient with MuSK-MG starting at 3.5years with ptosis as the sole symptom for 2years. A brief period of generalization was followed by complete stable remission for 6years. Prolonged ocular symptoms and long...
Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness, fatigability, and autoantibodies against protein antigens of the muscle endplate. Antibodies against acetylcholine receptor (AChR), and less frequently against muscle-Specific Kinase (MuSK) or lipoprotein related protein 4...
MuSK antibody-positive myasthenia gravis (MuSK-MG) accounts for 5 to 15% of autoimmune MG. MuSK and LRP4 are coreceptors for agrin in the signaling pathway that causes clustering of acetylcholine receptor (AChR). MuSK also anchors the acetylcholinesteras
Antigen-specific immunoadsorption of MuSK autoantibodies as a treatment of MuSK-induced experimental autoimmune myasthenia gravis Journal of Neuroimmunology, Volume 339, 2020, Article 577136 Konstantinos Lazaridis,…, Socrates J. Tzartos Cerebral folate deficiency: A report of two affected siblings Molecular...
Prepubertal anti-Musk positive myasthenia gravis with long remission 热度: MuSK–antibody positive pure ocular myasthenia gravis 热度: 相关推荐 / NEURALREGENERATlONRESEARCH Volume5,Issue23December2010 w⋯ 舢 Citethisarticleas:NeuralRegenRes.2010;5(23):1832—1835 Casereportofahealthy,elderlymanwi...
medicament,medication,medicinal drug,medicine- (medicine) something that treats or prevents or alleviates the symptoms of disease neostigmine,Prostigmin- a cholinergic drug (trade name Prostigmin) used to treat some ophthalmic conditions and to treat myasthenia gravis ...
In the autoimmune neuromuscular disease myasthenia gravis (MG), patients can have autoantibodies against the postsynaptic muscle-associated receptor tyrosine kinase (MuSK) [64]. Binding of patient-derived MuSK mAbs to the extracellular Ig-like 1 and 2 domains disrupted the clustering of acetylcholine ...
Myasthenia gravis with antibodies against the muscle-specific receptor tyrosine kinase (anti-MuSK) has been described as a subtype of disease with more localised clinical features and a poorer response to treatment than acetylcholine receptor antibody (anti-AChR)-positive patients. Few cases have been...
We report on a 56-year-old woman with muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia with predominant bulbar symptoms and respiratory insufficiency. Conventional immunosuppression (prednisolone, azathioprine, mycophenolate mofetil) could not maintain the clinical improvement ...
Myasthenia gravis anti-acetylcholine receptor skeletal muscle (anti-nicotinic AChRs) anti-muscle specific kinase (anti-MuSK) anti-LRP4 Neuromyelitis optica (Devic-Syndrom) anti-aquaporin 4 (AQP4) central nervous system (CNS) Ovarian insufficiency anti-HSP90, anti-HSPA5 ovaries Pemphigus foliaceu...