The latter type of autoantibodies correlates with histologic and clinical parameters of gastric mucosa atrophy. The gastric H,K-ATPase, which is known to be the autoimmune target in classical autoimmune gastritis, also represents a major autoantigen in atrophic H . pylori gastritis. Molecular mimicry...
This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastricAnti-Intrinsic Factor抗体mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene ...
Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain andAnti-Pepsinogen I抗体arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, ...
a region of chromosome 17q12-q21. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. It is also expressed in adenocarcinomas of the colon, stomach, pancreas and the bile system and is present in ...
Histological examination of gastric mucosa following ethanol showed significant lesions in the form of gastric pits with detachment of the surface epithelium; vacuolation of epithelial cells and elongation of microvessels. The changes were dose-dependently attenuated by B-Hb. The treatment of rats with...
The IIF test employs tissue sections of kidney encircled by stomach from rats or mice. These sections are reacted with the patient’s serum as above for theANA test. AMAs give granular reactivity with the cytoplasm of thekidney tubulesand cells within the gastricmucosa. ...
COX-1 is important in producing prostaglandins with physiological functions such as protection of the gastrointestinal mucosa and vascular homeostasis; its levels are reasonably constant. On the other hand, COX-2 is up-regulated at sites of inflammation and it is responsible for the production of ...
Regulate the normal secretion of hormones in the body; Control acid depletion in the body; Protect the skin mucosa and other functions, make the skin moist and healthy, so as to achieve the role of beauty and skin care; It can also improve the hair follicle...
Regression of hemangiomata in the gastric mucosa and skin was established. Her parents have a normal platelet count and mean platelet volume (MPV). There was never any sign of Kasabach-Merritt syndrome with normal fibrinogen and d-dimer levels. There was also no family history of an autoimmune...
Appears to be a novel specific biomarker for a cervical neoplasia. Tissue Specificity: Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa. Sequence Similarities: Belongs ...