Analyses were performed from whole blood samples of patients with seropositive RA (n = 108), seronegative RA as well as other rheumatic disorders (n = 122), and healthy blood donors (n = 200) and compared to detection via ELISA. Results Using the POCT, anti-MCV antibodies were detected ...
The level of anti-α-Enolase antibodies was nearly doubled in serum of ATAB-positive patients compared to ATAB-negative patients (7·04 ± 1·80 vs 3·68 ± 0·54 ng/ml, P = 0·007, student's t-test, Fig. 7a). Additionally, the level of anti-MCV antibodies ...
All patients were HLA class I genotyped to determine eligibility for CD8 T cell specific MCPyV-tetramer screening (Bloodworks Northwest, Seattle, WA). PBMC collected from patients with HLA class I (HLA-I) types that corresponded to available MCPyV-specific tetramers (A*02:01, A*24:02, B...
The red blood cell distribution width (RDW), a simple index in peripheral blood circulation, reflects the size heterogeneity of red blood cells, commonly used for differential diagnosis of anemia [26]. Several studies have demonstrated that elevated RDW is correlated with inflammatory status in vario...
(n = 3 mice). n.s., P > 0.05. RBC red blood cells, Hct hematocrit, Lym lymphocytes, Neu neutrophils, WBC white blood cells, Mon monocytes, Hgb hemoglobin, Eos eosinophils, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, ...
First, Evidence for immune activation in IPF pathogenesis is supported by the recent identification of a signature of 52 genes expressed by peripheral blood mononuclear cells significantly associated with transplant-free survival in IPF patients [9,10]. Decreased expression of genes belonging to the ...
VEGF165b in peripheral arterial disease in human and mouse Liang-Hui Chu1, Vijay Chaitanya Ganta2, Min H. Choi2, George Chen1, Stacey D. Finley3, Brian H. Annex2 & Aleksander S. Popel1 Angiogenesis is the growth of new blood vessels from pre-existing micro...
Serum glucose in a blood sample from the tail vein was measured using a glucometer at 60 min. The data are expressed as the means ± standard error of mean (SEM). Statistical comparisons were performed using a one-way ANOVA followed by the Student-Newman-Keuls test, and the differences ...
Moreover, since the commercial anti-CCP ELISA kit uses an even more stringent cut-off, corresponding to the 99th centile among 260 blood donors and the 98th centile among 521 disease controls, this actually strengthens the differences observed between anti-CCP antibodies and the ACPA fine ...
Table 4. Fluorophenyl imidazole effect on leukogram and blood count in mice exposed to the acute oral toxicity protocol (OECD 423). Group (treatment)Parameter Empty CellWBC (x 109/L)Lymphocytes (x 109/L)Monocytes (x 109/L)Granulocytes (x 109/L)RBC (x1012/L)HGB (g/L)HCT (%)MCV (...