et al. A novel anti-IL4Rα nanoparticle efficiently controls lung inflammation during asthma. Exp. Mol. Med. 48, e262 (2016).Halwani R, Sultana Shaik A, Ratemi E, Afzal S, Kenana R, Al-Muhsen S, Faraj AA (20160. A novel anti-IL4Rα nanoparticle efficiently controls lung ...
The release of anti-inflammatory drugs from a biomaterial has been proposed as a potential solution for several medical conditions such as rheumatic diseases, asthma/allergy, fibrotic diseases, and transplant rejection, but has also been proposed as a solution to suppressing a detrimental host response...
IL-4, IL-5, IL-13, andeotaxinlevels in the bronchoalveolar lavage fluid (BALF), as well as lung tissueeosinophiliaand airway mucus production, which are recognized as important clinical hallmarks in asthma patients. Meanwhile, the transcription levels of E-selectin, IL-17, IL-33, and Muc5ac...
DeCaterina, R. & Zampolli, A. From asthma to atherosclerosis-5-lipoxygenase, leukotrienes, and inflammation. N. Engl. J. Med. 350, 4–7 (2004). Article CAS Google Scholar Bäck, M. Leukotriene signaling in atherosclerosis and ischemia. Cardiovasc. Drugs Ther. 23, 41–48 (2009). Artic...
Hypercholesterolemia is a major risk factor in atherosclerosis development and lipid-lowering drugs (i.e., statins) remain the treatment of choice. Despite effective reduction of LDL cholesterol in patients, a residual cardiovascular risk persists in some individuals, highlighting the need for further ...
http://www.fda.gov/drugs/drugsafety/ucm414911.htm. Accessed Sept 29, 2014. Holgate STCA, Hebeft J. Efficacy and safety of a recombinant anti-immunoglobulin E antibody(omalizumab)in severe allergic asthma. Clin Exp Allergy J Br Soc Allergy Clin Immunol. 2004;34(4):632–8. Article CAS ...
Enterovirus 71 (EV71) is one of the causative agents of hand, foot, and mouth disease (HFMD), which sometimes leads to severe neurological disease and death in the Asia–Pacific region. In Chinese medicine, HFMD is caused mainly by an accumulation of dam
Additionally, in complex formulations of OM-3 fatty acids, high levels of palmitic acid could reduce the in vivo effect on crystal-mediated IL-1β elevation. OM-3 CA has a broadly efficacious anti-inflammatory effect with a strong exposure–response relationship that could be beneficial in ...
The release of anti-inflammatory drugs from a biomaterial has been proposed as a potential solution for several medical conditions such as rheumatic diseases, asthma/allergy, fibrotic diseases, and transplant rejection, but has also been proposed as a solution to suppressing a detrimental host response...
Methods for treating cancer comprising administering a DLL4 antagonist and one or more anti-hypertensive agents are described. Also described are pharmaceutical compositions compris