Zhang F, Huang G, Hu B, Fang LP, Cao EH, Xin XF, Harada H, Higashi T, Takagi R, Nakano K, et al. Anti-HMGB1 neutralizing antibody ameliorates neutrophilic airway inflammation by suppressing dendritic cell-mediated Th17 polarization. Mediat Inflamm. 2014;2014:257930....
Anti-HMGB1 Neutralizing Antibody Ameliorates Gut Barrier Dysfunction and Improves Survival after Hemorrhagic Shock 机译:抗HMGB1中和抗体改善失血性休克后肠屏障功能障碍并提高生存率 代理获取 本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但...
The secreted HMGB1 mediates various inflammatory diseases, including periodontitis; however, the underlying mechanisms of HMGB1-induced periodontal inflammation are not completely understood. Here, we examined whether anti-HMGB1 neutralizing anti- body inhibits periodontal progression and investigated the ...
Anti-HMGB1 Neutralizing Antibody Ameliorates Gut Barrier Dysfunction and Improves Survival after Hemorrhagic Shock KJ, Harbrecht BG, Billiar TR, Fink MP: Anti-HMGB1 neutralizing antibody ameliorates gut barrier Dysfunction and improves survival after hemorrhagic shock. Mo... R Yang,T Harada,KP Mollen,...
Antibody fragments which bind HMGB1 may also be employed, including Fab, Fab2, and single chain antibodies or their fragments. The invention concerns an in vitro method for quantitating antibodies, especially total antibodies, specific for HMGB1 contained in a cerebrospinal fluid sample obtained from ...
neutralizing antibody anti-HMGB1 in the treatment of lupus-prone BXSB mice can reduce the concentration of proteinuria, glomerulonephritis, circulating anti-dsDNA, immune complex deposition, and plasma cytokines22. HMGB1 can also be used as an autoantigen to directly stimulate the body to produce anti...
Recently, we found that the translocation and release of HMGB1 from neuronal nuclei to the extracellular space occurs both in ischemic and traumatic brain injuries, and that a neutralizing monoclonal antibody (mAb) against HMGB1 significantly ameliorates the resultant brain injuries by protecting against...
Inflammation plays a crucial role in kidney damage after crush syndrome (CS). Several researchers report that high mobility group box-1 protein (HMGB1) may be the vital trigger in kidney damage, and tumor necrosis factor-α (TNF-α) and c-Jun N-terminal
The high mobility group box-1 (HMGB1), originally identified as an architectural nuclear protein, exhibits an inflammatory cytokine-like activity in the extracellular space. Here we show that treatment with neutralizing anti-HMGB1 monoclonal antibody (mAb; 200 microg, twice) remarkably ameliorated brai...
Anti-HMGB1 Neutralizing Antibody Ameliorates Neutrophilic Airway Inflammation by Suppressing Dendritic Cell-Mediated Th17 Polarization Mediators of Inflammation . 2014Zhang F,Huang G,Hu B,et al.Anti-HMGB1 neutralizing antibody ameliorates neutrophilic airway inflammation by suppressing ... F Zhang,G Huang,...