GEREÇ VE YÖNTEM Çalışmamızda; 2003–2011 yılları içerisinde Cumhuriyet Üniversitesi Uygulama ve Araştırma Hastanesi'ne başvuran hastalardan alınan kan örneklerinin anti HCV test sonuçları geriye dönük olarak incelenmiştir. Ayrıca; Cumhuriyet ...
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IgG1 is also the most the prevalent isotope for hepatitis C (HCV) antigens, followed by IgG3, with IgG2 and IgG4 rarely occurring or not detected [99]. Moreover, in hepatitis B infection (HBV) [100], anti-HBs neutralizing antibodies are highly biased toward IgG1 and IgG3, with only...
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HCV infection is a major global health problem with an estimated 150–160 million people assumed to be infected, approximately 3% of the world's population [7,8]. Chronic hepatitis C leads to fibrotic changes in the liver, and ultimately to cirrhosis, after the development of which, the ...
Tetrazole and triazole as bioisosteres of carboxylic acid: Discovery of diketo tetrazoles and diketo triazoles as anti-HCV agents. Bioorg. Med. Chem. Lett. 2013, 23, 4528–4531. [CrossRef] [PubMed] 16. Patel, K.; Karthikeyan, C.; Solomon, V.R.; Moorthy, N.S.H.N.; Lee, H.; ...
The SAR indicated that: (i) the introduction of a thiadiazole on the 11-side chain was beneficial for activity; (ii) a 12-N-benzyl moiety was favorable for activity. Among them, compound 6n displayed a high activity with an inhibitory rate of 39.7% at a concentration of 40 µM. It ...
marine drugs Article Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice Chih-Hung Guo 1,2,*, Simon Hsia 2, Chieh-Han Chung 1,2, Yi-Chun Lin 1,2, Min-Yi Shih 1,2, Pei-Chung Chen ...