Anti-H3K9me3 monoclonal antibody 英文名称: Anti-H3K9me3 monoclonal antibody 总访问: 81 国产/进口: 进口 半年访问: 5 产地/品牌: BPS 产品类别: 其他生物试剂 规格: 50 μg 最后更新: 2024-12-5 货号: 25271 CAS 号: 参考报价: 5810 立即询价 电话咨询 ...
Anti-Histone H3K9me3 Antibody的详细介绍 Target Function:Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12...
Acetylation on Lys-10 (H3K9ac) impairs methylation at Arg-9 (H3R8me2s). Acetylation on Lys-19 (H3K18ac) and Lys-24 (H3K24ac) favors methylation at Arg-18 (H3R17me). Acetylation at Lys-123 (H3K122ac) by EP300/p300 plays a central role in chromatin structure: localizes at the ...
The histone mark of heterochromatin that is found near all of the centromeres (H3K9me3) is also lost, as is the heterochromatin protein 1a (Hp1a) which is also associated with pericentric heterochromatin. As a result of the loss of pericentric heterochromatin H3K9me3 and Hp1a, there is an ...
DNMT1 is directed towards replication foci through the interaction of its replication foci targeting sequence domain with the methylated histone H3K9me3 [83] whose distribution in the genome might not be uniform. Persistent methylation despite partial inhibition of DNMT1 could be due to an abundance...
Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L,et al. H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science. 2019;363:294-297pubmedpublisher immunohistochemistry - paraffin section; rat;loading ...; fig 2c ...
n = 3; αKG + DEG,n = 3.h, Representative western blots and log2fold change protein expression of H3K9me3 in human CD8+T cells treated with or without 500 µM DEG or 500 µM αKG for 7 days. Ordinary one-way ANOVA;n = 3–5. DEG,n = 11; α...
catalytic subunit of the prc2/eed-ezh2 complex, which methylates 'lys-9' (h3k9me) and 'lys-27' (h3k27me) of histone h3, leading to tranional repression of the affected target gene. able to mono-, di-and trimethylate 'lys-27' of histone h3 to form h3k27me1, h3k27me2 and h3...
Moreover, the examined DNMT inhibitor enhances certain gene transcription activation via chromatin remodelling – the changes in histone H3K4(Me)3 and H3K9Ac/S10P modifications were detected. Our results suggest, that DNMT inhibitor – procaine, can be used for further investigations on epigenetic ...
H3K9me3 could also control ISGs indirectly, for example through regulation of expression of transposable elements (TEs), which in turn drive IFN-signaling. Indeed, Suv39h1 was shown to control expression of several families of TEs in fibroblasts and RNA from TEs can be sensed in the cytosol ...