Anti-drug antibodies may also increase the risk of hypersensitivity reactions by the formation of immune complexes. Furthermore, by cross-reacting with the endogenous homolog of the drug, the anti-drug antibodies might impair important physiological functions even after treatment cessation. As a ...
求翻译:anti-drug antibodies是什么意思?待解决 悬赏分:1 - 离问题结束还有 anti-drug antibodies问题补充:匿名 2013-05-23 12:21:38 抗药物抗体 匿名 2013-05-23 12:23:18 反对服用麻醉品的抗体 匿名 2013-05-23 12:24:58 反药物抗体 匿名 2013-05-23 12:26:38 正在翻译,请等待... 匿...
Immunogenicity testing is an essential step in therapeutic protein drug development process. Anti-Drug antibodies (ADA) may lead to many clinical problems including allergic reactions, altered pharmacokinetic, reduced efficacy, etc. Thus, immunogenicity testing to evaluate the ADA level induced by therapeu...
但是因为免疫源性强,产生人抗小鼠抗体(human anti‐murine antibodies ,HAMA), 导致快速的药物清除,半衰期只有几个小时到十几个小时,限制了临床使用。 影响抗体药物ADA(Anti-Drug antibody)产生的因素mp.weixin.qq.com/s/VZidrEghK9gCUusOKK1K4g 之后,为了降低免疫原性,先后开发了嵌合体抗体,人源化抗体和全...
However, many reasons still limit their usage, and one of them is related to their immunogenicity, namely, the immune system may react against these biological molecules by producing anti-drug antibodies (ADAs). ADAs may lead to allergic reactions, altered pharmacokinetics and reduced efficacy. The...
antidrug 听听怎么读 英['ænti:drʌɡ] 美['æntidrʌɡ] 是什么意思 adj. 反对服用麻醉品的; 学习怎么用 权威例句 Antidrug antibodies in psoriasis: a systematic review Effects of Gain Versus Loss Frame Antidrug Ads on Adolescents
Biologic drugs have transformed the standard of care for many diseases. However, many biologics induce the formation of anti-drug antibodies (ADAs), which can compromise their safety and efficacy. Preclinical studies demonstrate that biodegradable nanopa
Define antidrug. antidrug synonyms, antidrug pronunciation, antidrug translation, English dictionary definition of antidrug. adj. Directed against the production, distribution, and use of illegal drugs. American Heritage® Dictionary of the English Lan
Antibodies against dietary antigens in rheumatoid arthritis patients treated with fasting and a one-year vegetarian diet. Clin. Exp. Rheumatol. 13, 167–172 (1995). CAS PubMed Google Scholar Haqq, A. M. et al. Ghrelin concentrations in Prader–Willi syndrome (PWS) infants and children: ...
Anti-drug antibodies Incidence of ADAs Subjects were divided into four TE-ADA analysis populations depending on their maximum TE-ADA titer reached during 60 weeks of treatment. Titer subgroups included TE-ADA negative, TE-ADA low (maximum titer < 1:160), TE-ADA moderate (maximum titer ≥ 1:...