The absolute configuration of anti-Vibrio citrinin dimeric derivative by VCD, ECD and NMR methods.doi:10.1080/14786419.2018.1493590Fei CaoTian-Tian SunJian-Kun YangGuo-Zheng ZhaoQing-Ai LiuLian-Dong HuZheng-Yue MaHua-Jie ZhuTaylor & Francis...
Sludge characteristics are closely related to the secondary structures of surface proteins, which play a key role in membrane fouling [60]. A detailed analysis of EPS secondary structures was conducted by focusing on the derivative spectra (Figure S5 and Table 1). Amide I in the EPS contained ...
7 The ID8 mouse ovarian cancer cell line and its Vegf-a-overexpressing derivative (ID8-Vegf) were kindly provided by Dr Katherine Roby on September 2009. These cells were cultured and maintained in RPMI1640 (Invitrogen, Carlsbad, CA, USA) supplemented with 10% foetal bovine serum (FBS), ...
In the present study, we report the signaling properties of I-287, a bicyclic heteroaryl derivative developed by Vertex Pharmaceuticals and described in the patent WO201615407522. Using bioluminescence resonance energy transfer (BRET)-based assays that allow direct monitoring of the engagement and activa...
6 439.8 8.35 Coumaric acid derivative – 7 555.8 10.92 Tetra-hydroxy-stilbene galloyl Hexoside – 8 593.3 11.53 Luteolin-glycopyranosyl-rhamnopyranoside – 9 601.2 11.92 Rutin Rutin 10 701.5 13.94 Geraniin isomer derivative Geraniin isomer derivative The chromatogram in Fig. 1(a) shows the existence...
All the anti-inflammatory sources or drugs achieve their effects by blocking the increase in prostaglandin (PG) synthesis. PG synthesis is blocked by blocking the enzyme cyclooxygenase – an enzyme in arachidonic acid cascade for the synthesis of prostan
The new antibacterial bicyclic terpene derivative clathric acid (78) was obtained from the methanolic extract of the spongeClathria compressa, collected at Panama City, Florida (USA), along with two newN-acyl taurine derivatives clathrimides A and B. Only clathric acid (78) exhibited antibacter...
On the other hand, the 4-hydroxybenzoic acid derivative 4e (entry 5) was potent and had an IC50 of 1.72 mM, while its methylated analog 4d (entry 4) completely lost anti-invasive activity. This stressed the subtle bulkiness or polarity requirements at the 4-position of the phenyl ring. ...
DMF5 is specific to three MART-1 peptides, including a synthetic derivative peptide (ELAGIGILTV (ELA)), which induces the strongest activation. In addition, we generated Jkt-DMF5 cell lines expressing the previously described mutations in the alpha connecting peptide motif (aCPM) (Jkt-DMF5...
PGF2 -ethyl ester derivative (27) (1.405 g) was dissolved in a mixted solvent (50 ml) of THF-CH2 Cl2 (2:5). To the solution was added a THF-CH2 Cl2 (2:5; 20 ml) solution of NBS (0.5250 g) at 0° C., which was agitated for 20 min. A crude product obtained after the us...