the invention relates to a method for determining a bone marrow failure disorder of a subject or the absence thereof, or subclassifying a subject having a bone marrow failure disorder, or to a method for determining a specific autoantibody or a polynucleotide encoding said autoantibody or a fragme...
Myositis autoantibody inhibits histidyl-tRNA synthetase: a model for autoimmunity In autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus (SLE), autoantibodies are generated against a variety of macromolecul... MB Mathews,RM Bernstein - 《Nature》 被引量: 668发表: 1983年...
Subsequently, differences in the proportion of patients achieving DFR and using biologicals were analysed using Cox-proportional hazard models. Kaplan Meier curves and analyses were stratified for IgG ACPA and IgM RF, because DFR and biological usage rates are different for autoantibody positive and ...
Only certain COX-2 inhibitors block pathogenic anti-DNA autoantibody production in lupus by causing death of autoimmune T helper cells. Hence COX-2 ... SK Datta,Z Li,L Xu - 《Journal of Molecular Medicine》 被引量: 95发表: 2005年 加载更多来源...
Fig. 3. Cox Proportional Hazards model of survival for different sub-groups. Ab; autoantibody present, COP; Cryptogenic organising pneumonia without an autoantibody present, IPF; Idiopathic Pulmonary Fibrosis without an autoantibody present, NSIP; Non-specific interstitial Pneumonia without an autoantibody...
Define antiinflammatory. antiinflammatory synonyms, antiinflammatory pronunciation, antiinflammatory translation, English dictionary definition of antiinflammatory. antiinflammatory. Translations. English: antiinflammatory adj & n antiinflamatorio. Spani
In Multivariable Cox regression analysis, variables potentially acting as confounders are excluded from the final model. We conclude that although the prevalence of anti-NCS positivity is low in patients with inactive SLE, the presence of positivity for this autoantibody increases the risk of renal ...
Multivariate Cox regression analysis of influencing factors of progression-free survival in lung cancer patients treated with PD-1/PD-L1 inhibitors. 1-year PFS1.5-year PFS2-year PFS Events/patientsHazard ratio (95 % CI)p-ValueEvents/patientsHazard ratio (95 % CI)p-ValueEvents/patientsHazard...
M Dugar,S Cox,V Limaye,... - 《Internal Medicine Journal》 被引量: 65发表: 2011年 Clinical profile of anti-PL-12 autoantibody. Cohort study and review of the literature. The antisynthetase syndrome consists of interstitial lung disease, arthritis, myositis, fever, mechanic's hands, and Ra...
Indeed, they produce cytokines helping autoantibody production by B cells, and also fibrogenic mediators such as IL-10, TGF-β 1 or TNF-α [13,14]. Fourth, CD4 T cells purified from lymph nodes from IPF patients proliferate when cultured with autologous lung tissue protein extracts [13]. ...